An intrafascicular electrode for recording of action potentials in peripheral nerves
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We are developing a new type of bipolar recording electrode intended for implantation within individual fascicles of mammalian peripheral nerves. In the experiments reported here we used electrodes fabricated from 25 μm diameter Pt wire, 50 μm 90% Pt-10% Ir wire and 7 μm carbon fibers. The electrodes were implanted in the sciatic nerves of rats and in the ulnar nerves of cats. The signal-to-noise ratio of recorded activity induced by nonnoxious mechanical stimulation of the skin and joints was studied as a function of the type of electrode material used, the amount of insulation removed from the recording zone, and the longitudinal separation of the recording zones of bipolar electrode pairs. Both acute and short term (two day) chronic experiments were performed.
The results indicate that a bipolar electrode made from Teflon™-insulated, 25 μm diameter, 90% Pt-10% Ir wire, having a 1–2 mm long recording zone, can be used for recording of peripheral nerve activity when implanted with one wire inside the fascicle and the other lead level with the first lead, but outside the fascicle. No insulating cuff needs to be placed around the nerve trunk.
KeywordsNeuroprosthesis Peripheral nerve electrodes Sensory recording
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- 3.de Boer, R.W.; van Oosterom, A. Electrical properties of platinum electrodes: impedance measurements and time-domain analysis. Med. & Biol. Eng. & Comput. 16:1–10; 1978.Google Scholar
- 5.Hambrecht, F.T. Neural prostheses. Ann. Rev. Biophys. Bioeng. 8:239–267; 1979.Google Scholar
- 7.Holle, J.; Frey, M.; Gruber, H.; Stoehr, H.; Toma, H. Functional electrical stimulation of paraplegics. Experimental investigations and first clinical experience with an implantable stimulation device. Orthopedics 7:1146–1155; 1984.Google Scholar
- 9.Kao, C.C.; Wrathall, J.R.; Kyoshima, K. Rationales and goals of spinal cord reconstruction. In: Spinal Cord Reconstruction, Kao, C.C.; Bunge, R.P.; Reier, P. J., eds. New York: Raven Press; 1983; pp. 1–6.Google Scholar
- 10.Kralj, A.; Bajd, T.; Turk, R.; Krajnik, J.; Benko, H. Gait restoration in paraplegic patients: a feasibility demonstration using multichannel surface electrode FES. J. Rehab. Res. Dev. 20:3–20; 1983.Google Scholar
- 14.Marsolais, E.B. Stages in the development of useful FNS-augmented walking. RESNA Proc. 9th Annl. Conf. Rehab. Techn. 9:279–281; 1986.Google Scholar
- 15.Pattle, R.E. The external action potential of a nerve or muscle fiber in an extended medium. Physics Med. Biol. 16:673–685; 1971.Google Scholar
- 18.Stoehr, H.M.; Bochdansky, T.; Frey, M.; Holle, J.; Kern, H.; Schwanda, G.; Thoma, H. Functional electrostimulation makes paraplegic patients walk again. In: 1st Vienna International Workshop on Functional Electrostimulation. Vienna, Austria: Bioengineering Lab. Van Swieten-Gasse, Austria, 1983; p. 5.4.Google Scholar
- 19.Sunderland, S. Nerves and nerve injuries. Baltimore: Williams and Wilkins; 1968.Google Scholar
- 21.Weinman, J.; Mahler, J. An analysis of electrical properties of metal electrodes. Med. Electron. & Biol. Eng. 2:299–310; 1964.Google Scholar
- 22.Yonezawa, Y.; Ninomiya, I.; Nishiura, N. A printed implantable electrode for recording neural signals in awake animals. IEEE/Ninth Ann. Conf. Eng. Med. Biol. Soc. Ch2513:485–487; 1987.Google Scholar