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Annals of Biomedical Engineering

, Volume 15, Issue 5, pp 419–426 | Cite as

Development of a platinized platinum/iridium electrode for use in vitro

  • Kenneth R. Cote
  • Richard C. Gill
Article

Abstract

Silver/silver chloride (Ag/AgCl) electrodes possess excellent electrical properties for measuring the electrical activity of gastrointestinal smooth muscle but exert toxic effects on this tissue in vitro. We thus developed a platinum electrode for use in vitro, the construction of these electrodes relying upon the formation of a glass-platinum/iridium seal. The platinum/iridium (Pt/Ir) electrodes were platinized using a current density of 0.45 mA mm−2. The electrode impedance at 0.01 Hz showed a minimum with platinization current-time products greater than 500 mA s mm−2. However, deposits in excess of 600 mA s mm−2 were readily removed by mechanical abrasion and proved unsatisfactory. Optimal platinization was obtained with a deposit of platinum-black corresponding to a current-time product of 550 mA s mm−2. Optimally-platinized electrodes (geometric surface area 0.11 mm2) had a stable and reproducible potential with a drift of less than 1 μV min−1 and a lower impedance than optimally chlorided silver electrodes (geometric surface area 0.46 mm2) at frequencies higher than 0.25 Hz. The platinized Pt/Ir electrodes were used to record the electrical activity of gastrointestinal smooth muscle in vitro.

Keywords

Platinum/iridium electrodes Biological electrodes Platinization 

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References

  1. 1.
    Becker, J.M., W.M. Duff, F.G. Moody. Myoelectric control of gastrointestinal and biliary motility: a review.Surgery 89:466–477, 1981.PubMedGoogle Scholar
  2. 2.
    Cole, K.S. and U. Kishimoto. Platinized silver chloride electrode.Science 136:381–382, 1962.PubMedGoogle Scholar
  3. 3.
    Daniel, E.E.. Electrical activity of the gastrointestinal tract as an indication of mechanical activity.Am. J. Dig. Dis. 8:54–102, 1963.CrossRefPubMedGoogle Scholar
  4. 4.
    de Boer, R.W. and van Oosterom. Electrical properties of platinum electrodes: impedance measurements and time-domain analysis.Med. & Biol. Eng. & Comput. 16:1–10, 1978.Google Scholar
  5. 5.
    El-Sharkawy, T.Y. Electrical activities of the muscle layers of the canine colon.J. Physiol. 342:67–83, 1983.PubMedGoogle Scholar
  6. 6.
    Fisher, G., R.G. Sayre, R.G. Bickford. Histological changes in cat's brain after introduction of metallic and coated wire used in electroencephalography.Proc. Mayo Clic. 32:14–21, 1957.Google Scholar
  7. 7.
    Gill, R.C., K.R. Cote, K.L. Bowes, Y.J. Kingma. Human colonic smooth muscle: electrical and contractile activity in vitro.Gut 27:293–299, 1986.PubMedGoogle Scholar
  8. 8.
    Hinder, R.A. and K.A. Kelly. Human gastric pacesetter potential. Site of origin, spread and response to gastric transection and proximal gastric vagotomy.Am. J. Surg. 133:29–33, 1977.CrossRefPubMedGoogle Scholar
  9. 9.
    Jackson, W.F. and B.R. Tuling Toxic effects of silver/silver chloride electrodes on vascular smooth muscle.Circ. Res. 53:105–108, 1983.PubMedGoogle Scholar
  10. 10.
    Jones, G. and G.M. Bollinger. The measurement of the conductance of electrolytes. VII on platinization.J. Am. Chem. Soc. 57:280–284, 1935.Google Scholar
  11. 11.
    Kingma, Y.J., J. Lenhart, N.G. Durdle, K.L. Bowes, M.M. Chambers. Improved Ag/AgCl pressure electrodes.Med. & Biol. Eng. & Comput. 21:351–357, 1983.Google Scholar
  12. 12.
    Kohlrausch, F. Uber platinirte Elektroden und Widerstandsbestimmung.Ann. Phys. Chem. 60:315–332, 1897.Google Scholar
  13. 13.
    Lukanov, J. and P. Atmadjov. Investigating the effect of silver ions on the contractile function of smooth-muscle preparation from guinea pig stomach in vitro.Folia Med. (Plovdiv) 21:11–19, 1979.Google Scholar
  14. 14.
    Onaral, B. and H.P. Schwan. Linear and onlinear properties of platinum electrode polarization. Part 1: frequency dependence at very low frequencies.Med. & Biol. Eng. & Comput. 20:299–306, 1982.Google Scholar
  15. 15.
    Petering, H.G. Pharmacology and toxicology of heavy metals: Silver.Pharmacol. Ther. 1:127–130, 1976.Google Scholar
  16. 16.
    Ray, C.D. and A.E. Walker. Platinized platinum wire brain depth probes: a comparison with electrodes of stainless steel.Proc. Am. EEG Soc. 19:90–91, 1965.Google Scholar
  17. 17.
    Schwan, H.P. Determination of biological impedances. In: Physical Techniques in Biological Research, Vol. 6. Nastuk, W.L. (Ed.), New York: Academic Press, 323–407, 1963.Google Scholar
  18. 18.
    Schwan, H.P. Electrode polarization impedance and measurement in biological materials.Ann. N.Y. Acad. Sci. 148:191–209, 1968.PubMedGoogle Scholar
  19. 19.
    Warburg, E. Ueber das Verhalten sogenanten und polisierbarer Electroden gegen Wechselstrom.Ann. Phy. Chem. 67:493–499, 1899.Google Scholar

Copyright information

© Pergamon Journals Ltd 1987

Authors and Affiliations

  • Kenneth R. Cote
    • 1
  • Richard C. Gill
    • 1
  1. 1.Department of SurgeryUniversity of AlbertaEdmontonCanada

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