Journal of Orthopaedic Science

, Volume 1, Issue 3, pp 203–213 | Cite as

Anterior cruciate ligament reconstruction using iliotibial tract: Histological and mechanical studies in rabbits

  • Masayuki Minamide
  • Hideshige Moriya
  • Akihiro Tsuchiya
Original Articles


A histological and biomechanical study of anterior cruciate ligament (ACL) reconstruction using the iliotibial tract (ITT) was carried out in rabbits. Sixty-five young adult male rabbits were used for the experiments. In the histological study, 3 weeks after the substitution, specimens, showed acellular changes, and cellular repopulation was noted from the peripheral area at 6 weeks. At 24 weeks, the original spindle-shaped fibroblasts of the substitute had changed to round cells. The ligament bone junction was formed by 48 weeks and its structure was similar to that of a normal junction. Transmission electron microscopic examination showed collagen fibril distribution in each test group. The 12-week specimens had fibrils of small diameter only, but some 24-week specimens showed a biphasic appearance, like the ACL, which has both large and small fibrils. On mechanical testing, the maximal load was decreased until 18 weeks, and then recovered to 50% of that of the normal ACL at 48 weeks, this value being approximately the same as that of the ITT used in the reconstruction.

Key words

anterior cruciate ligament reconstruction experimental study ihotibial tract histological maturation biomechanical property 


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Copyright information

© The Japanese Orthopaedic Association 1996

Authors and Affiliations

  • Masayuki Minamide
    • 1
  • Hideshige Moriya
    • 1
  • Akihiro Tsuchiya
    • 1
  1. 1.Department of Orthopaedic Surgery, School of Medicinethe University of ChibaChibaJapan

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