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Increased glucagon secretion during hyperthermia in a sauna

  • P. Tatár
  • M. Vigaš
  • J. Jurčovičová
  • R. Kvetňanský
  • V. štrec
Article

Summary

Plasma glucagon, adrenaline, noradrenaline, insulin and glucose concentrations were measured in 7 healthy young males during hyperthermia in a sauna bath: plasma glucagon levels increased from baseline values of 127.0±12.9 (SEM) pg · ml−1 to a maximum of 173.6±16.1 (SEM) pg · ml−1 at the 20th min of exposure. No change in plasma insulin and a slight increase in plasma glucose concentration were seen. Since a concomitant moderate increase in plasma catecholamine levels was also present, the adrenergic stimulus is believed to trigger glucagon release during hyperthermia. Diminished visceral blood flow, known to occur in sauna baths, may cause a decrease in the degradation of plasma glucagon and thus contribute to the elevated plasma glucagon levels.

Key words

Glucagon Hyperthermia Catecholamines Insulin Glucose 

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References

  1. Fritsche I, Fritsche W (1980) Die wissenschaftlichen Grundlagen des Saunabades. Sauna-Archiv 4, 80:1–64Google Scholar
  2. Jurčovičová J, Vigaš M, Palát M, JeŽová D, Klimeš I (1980) Effect of endogenous GH secretion during hyperthermic bath on glucose metabolism and insulin release in man. Endocrinol Exp 14:221–226PubMedGoogle Scholar
  3. Kampa IS, Frascella DW, Hundertmark JM, Rosenberg JM, Reid V (1981) The effect of hyperthermic stress on blood glucagon levels in normal and diabetic rats. Horm Metab Res 13:122PubMedGoogle Scholar
  4. Lammintausta R, SyvÄlahti E, Pekkarinen A (1976) Change in hormones reflecting sympathetic activity in the finnish sauna. Ann Clin Res 8:266–271PubMedGoogle Scholar
  5. Peuler JD, Johnson GA (1977) Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. Life Sci 21:625–636CrossRefPubMedGoogle Scholar
  6. Tatár P, Vigaš M, Jurčovičová J, JeŽová D, štrec V, Palát M (1985) Impaired glucose utilization in man during acute exposure to environmental heat. Endocrinol Exp 19:277–281PubMedGoogle Scholar
  7. Unger RH (1983) Insulin-glucagon relationship in the defence against hypoglycemia. Diabetes 32:575–583PubMedGoogle Scholar
  8. Unger RH, Orci L (1976) Physiology and pathophysiology of glucagon. Physiol Rev 56:778–826PubMedGoogle Scholar
  9. Zierden E, Wagner H, Wüst G, Baumeister G, Hauss WH (1975) Human growth hormone, corticoids, insulin and glucose in serum during excessive hyperthermia and effect of somatostatin in male volunteers. Acta Endocrinol [Suppl] 193:73 (Abstr)Google Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • P. Tatár
    • 1
  • M. Vigaš
    • 2
  • J. Jurčovičová
    • 2
  • R. Kvetňanský
    • 2
  • V. štrec
    • 1
  1. 1.Research Institute for Human BioclimatologyCzechoslovakia
  2. 2.Institute of Experimental EndocrinologySlovak Academy of SciencesBratislavaCzechoslovakia

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