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Plasma norepinephrine and heart rate dynamics during recovery from submaximal exercise in man

  • Renza Perini
  • Claudio Orizio
  • Alessandro Comandè
  • Maurizio Castellano
  • Marina Beschi
  • Arsenio Veicsteinas
Article

Summary

The time course of heart rate (HR) and venous blood norepinephrine concentration [NE], as an expression of the sympathetic nervous activity (SNA), was studied in six sedentary young men during recovery from three periods of cycle ergometer exercise at 21%±2.8%, 43%±2.1% and 65%±2.3% of\(\dot V_{o_{2max} } \) respectively (mean±SE). The HR decreased mono-exponentially withτ values of 13.6±1.6 s, 32.7±5.6 s and 55.8±8.1s respectively in the three periods of exercise. At the low exercise level no change in [NE] was found. At medium and high exercise intensity: (a) [NE] increased significantly at the 5th min of exercise (Δ[NE]=207.7±22.5 pg·ml−1 and 521.3±58.3 pg·ml−1 respectively); (b) after a time lag of 1 min [NE] decreased exponentially (τ=87 s and 101 s respectively); (c) in the 1st min HR decreased about 35 beats · min−1; (d) from the 2nd to 5th min of recovery HR and [NE] were linearly related (100 pg·ml−1Δ[NE]5 beats ·min−1). In the 1st min of recovery, independent of the exercise intensity, the adjustment of HR appears to have been due mainly to the prompt restoration of vagal tone. The further decrease in HR toward the resting value could then be attributed to the return of SNA to the pre-exercise level.

Key words

Heart rate Norepinephrine Recovery Exertion 

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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Renza Perini
    • 1
  • Claudio Orizio
    • 1
  • Alessandro Comandè
    • 1
  • Maurizio Castellano
    • 2
  • Marina Beschi
    • 2
  • Arsenio Veicsteinas
    • 1
  1. 1.Institute of Physiology, Department of Biomedical Sciences and BiotechnologiesUniversity of BresciaBresciaItaly
  2. 2.Institute of Internal Medicine, Department of Medical SciencesUniversity of BresciaItaly

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