, Volume 31, Issue 10, pp 1202–1203 | Cite as

Depletion of heart norepinephrine in experimental acute myocarditis caused byTrypanosoma cruzi

  • A. B. M. Machado
  • C. R. S. Machado
  • C. B. Gomes


The norepinephrine content of the heart was reduced to undetectable values in rats inoculated withTrypanosoma cruzi. This fact indicates a massive involvement of the cardiac postganglionic sympathetic fibres in acute Chagas disease.


Norepinephrine Myocarditis Sympathetic Fibre Acute Myocarditis Norepinephrine Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    F. Köberle, Adv. Parasit.6, 63 (1968).Google Scholar
  2. 2.
    F. Köberle, Wien klin. Wschr.68, 333 (1956).PubMedGoogle Scholar
  3. 3.
    W. L. Tafuri, Am. J. tropic. Med. Hyg.19, 405 (1970).Google Scholar
  4. 4.
    F. Köberle, Münch. med. Wschr.101, 1308 (1959).Google Scholar
  5. 5.
    F. G. Alcantara, Z. tropenmed. Parasit.10, 296 (1959).Google Scholar
  6. 6.
    W. L. Tafuri andP. Raso, Hospital, Rio de J.62, 1325 (1962).Google Scholar
  7. 7.
    A. H. Anton andD. F. Sayre, J. Pharmac. exp. Ther.138, 360 (1962).Google Scholar
  8. 8.
    M. Holzbauer andD. F. Sharman inHandbook of Experimental Pharmacology, Catecholamines (Springer-Verlag, New York 1968), vol. 33, p. 110.Google Scholar
  9. 9.
    T. Tomomatsu, Jap. Circulation J.35, 979 (1971).Google Scholar
  10. 10.
    C. A. Chidsey andE. Braunwald, Pharmac. Rev.18, 685 (1966).Google Scholar
  11. 11.
    K. E. Mott andJ. W. C. Hagstrom, Circulation31, 273 (1965).PubMedGoogle Scholar
  12. 12.
    A. L. Ferreira andM. A. Rossi, Revta Inst. Med. trop. S. Paulo73, 391 (1971).Google Scholar
  13. 13.
    U. Trendelenburg andJ. S. Gravenstein, Science128, 901 (1958).PubMedGoogle Scholar
  14. 14.
    D. S. Amorim, R. A. Godoy, J. C. Manço, A. Tanaka andL. Gallo, Jr., Arquiv. brasil. Cardiol.21, 1 (1968).Google Scholar
  15. 15.
    S. J. Sarnoff, S. K. Brockman, J. P. Gilmare, R. J. Linden andJ. H. Mitchell, Circulation Res.8, 1108 (1960).PubMedGoogle Scholar
  16. 16.
    F. S. Laranja, E. Dias, G. Nobrega andA. Miranda, Circulation14, 1035 (1956).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1975

Authors and Affiliations

  • A. B. M. Machado
    • 1
    • 2
  • C. R. S. Machado
    • 1
    • 2
  • C. B. Gomes
    • 1
    • 2
  1. 1.Department of Morphology, Institute of Biological SciencesUniversity of Minas GeraisBelo HorizonteBrazil
  2. 2.Department of Biochemistry and PharmacologyEscola Paulista de MedicinaSão PauloBrazil

Personalised recommendations