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Chromatographia

, Volume 28, Issue 3–4, pp 193–196 | Cite as

Design of enzyme reactors as chromatographic columns for racemic resolution of amino acid esters

  • J. Kalbé
  • H. Höcker
  • H. Berndt
Originals

Summary

Racemic resolution of aromatic and aliphatic amino acid esters into L-amino acid and D-amino acid ester via LC and HPLC is achieved by using enzyme reactors as chromatographic columns. For this purpose α-chymotrypsin and trypsin are immobilized on Eupergit C, Sepharose 4B and Lichrosorb-Diol.

Key Words

Column liquid chromatography Chiral stationary phases Immobilized enzymes Racemic resolution of amino acid esters 

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References

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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • J. Kalbé
    • 1
  • H. Höcker
    • 1
  • H. Berndt
    • 1
  1. 1.Lehrstuhl für Textilchemie und Makromolekulare Chemie der RWTH AachenAachenFRG

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