Chromatographia

, Volume 28, Issue 3–4, pp 126–128

Preparative isolation of (+)-beta-eudesmol fromAmyris balsamifera

  • T. A. van Beek
  • R. Kleis
  • G. P. Lelyveld
  • AE. de Groot
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Summary

Optically pure (+)-beta-eudesmol is a possible starting material for the synthesis of several termite defense compounds. A two step procedure for the isolation of gram quantities of (+)-beta-eudesmol from commercially availableAmyris balsamifera oil (syn. West Indian sandalwood oil), containing 8% beta-eudesmol, was developed. Step one consisted of an efficient vacuum distillation of the total oil. Step two was a medium pressure LC separation with an AgNO3 impregnated silica gel stationary phase. Several other separation procedures failed due to the presence of many closely related sesquiterpene alcohols (75% of the oil).

Key Words

Column liquid chromatography Preparative isolation (+)-Beta-eudesmol Amyris balsamifera 

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References

  1. [1]
    R. Kesselmans, J.P.B.A. Wijnberg andAE. de Groot, in preparation to be submitted for publication in J. org. Chem.Google Scholar
  2. [2]
    T.A. van Beek, R. Kleis, M.A. Posthumus andA. van Veldhuizen, Phytochemistry (1989) in press.Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • T. A. van Beek
    • 1
  • R. Kleis
    • 1
  • G. P. Lelyveld
    • 1
  • AE. de Groot
    • 1
  1. 1.Department of Organic Chemistry, Phytochemical SectionAgricultural UniversityWageningenThe Netherlands

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