Preparative isolation of (+)-beta-eudesmol fromAmyris balsamifera
- 74 Downloads
Optically pure (+)-beta-eudesmol is a possible starting material for the synthesis of several termite defense compounds. A two step procedure for the isolation of gram quantities of (+)-beta-eudesmol from commercially availableAmyris balsamifera oil (syn. West Indian sandalwood oil), containing 8% beta-eudesmol, was developed. Step one consisted of an efficient vacuum distillation of the total oil. Step two was a medium pressure LC separation with an AgNO3 impregnated silica gel stationary phase. Several other separation procedures failed due to the presence of many closely related sesquiterpene alcohols (75% of the oil).
Key WordsColumn liquid chromatography Preparative isolation (+)-Beta-eudesmol Amyris balsamifera
Unable to display preview. Download preview PDF.