Annals of Surgical Oncology

, Volume 5, Issue 7, pp 603–606 | Cite as

Patient regrets after bilateral prophylactic mastectomy

  • Patrick I. Borgen
  • Arnold D. K. Hill
  • Katherine N. Tran
  • Kimberly J. Van Zee
  • Mary J. Massie
  • David Payne
  • Carina G. Biggs
Original Articles

Abstract

Background: The discovery of a cadre of breast cancer susceptibility genes has resulted in an increase in the number of women seeking information about prophylactic breast surgery, but virtually no large-scale prospective databases exist to assist women considering prophylactic mastectomy.

Methods: The authors constructed a National Prophylactic Mastectomy Registry comprised of a volunteer population of 817 women from 43 states who have undergone prophylactic mastectomy.

Results: In the registry, 370 women had undergone bilateral prophylactic mastectomy. Twenty-one (5%) women expressed regrets about the procedure. The median follow-up was 14.6 years (mean 14.8 years; range 0.2–51 years). Those with regrets were subsetted into those with major (n=10) or minor (n=7) regrets. Regrets were more common in those women with whom discussion about prophylactic mastectomy was initiated by a physician (19/255), compared with patients who initiated the discussion themselves (2/108;P<.05).

Conclusions: The overall satisfaction rate of 95% reported here may be explained by the voluntary nature of this registry. The most important factor that predicts an unfavorable outcome following bilateral prophylactic mastectomy is a physician-initiated discussion.

Key Words

Breast cancer Genetics Prophylactic mastectomy 

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Copyright information

© The Society of Surgical Oncology, Inc. 1998

Authors and Affiliations

  • Patrick I. Borgen
    • 2
  • Arnold D. K. Hill
    • 2
  • Katherine N. Tran
    • 2
  • Kimberly J. Van Zee
    • 2
  • Mary J. Massie
    • 1
  • David Payne
    • 1
  • Carina G. Biggs
    • 2
  1. 1.Department of PsychiatryMemorial Sloan-Kettering Cancer CenterNew York
  2. 2.Breast Service, Dept. of SurgeryMemorial Sloan-Kettering Cancer CenterNew York

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