Free radical formation and oxidative damage in rat tissue
Abstracts of Dutch Ph.D. Theses
- 20 Downloads
Key words
Anoxia Biotransformation Calcium paradox Doxorubicin Free radicals Ischemia Vitamin EResults are also published in the following papers
- Julicher RHM, Sterrenberg L, Koomen JM, Bast A, Noordhoek J. Evidence for lipid peroxidation during the calcium-paradox in vitamin E-deficient rat heart. Naunyn Schmiedebergs Arch Pharmacol 1984;326:87–9.CrossRefPubMedGoogle Scholar
- Julicher RHM, Tijburg LBM, Sterrenberg L, Bast A, Koomen JM, Noordhoek J. Decreased defence against free radicals in rat heart during normal reperfusion after hypoxic, ischaemic and calcium-free perfusion. Life Sci 1984;35:1281–8.CrossRefPubMedGoogle Scholar
- Sterrenberg L, Julicher RHM, Bast A, Noordhoek J. Adriamycin stimulates NADPH-dependent lipid peroxidation in liver microsomes not only by enhancing the production of O2−· and H2O2, but also by potentiating the catalytic activity of ferrous ions. Toxicol Lett 1984;22:153–9.CrossRefPubMedGoogle Scholar
- Julicher RHM, Sterrenberg L, Haenen GRMM, Bast A, Noordhoek J. Sex differences in the cellular defence system against free radicals from oxygen or drug metabolites in rat. Arch Toxicol 1984;56:83–6.CrossRefPubMedGoogle Scholar
- Julicher RHM, Van der Laarse A, Sterrenberg L, Bloys van Treslong CHF, Bast A, Noordhoek J. The involvement of an oxidative mechanism in the adriamycin-induced toxicity in neonatal rat heart cell cultures. Res Commun Chem Pathol Pharmacol 1985;47:35–47.PubMedGoogle Scholar
- Sterrenberg L, Julicher RHM, Bast A, Noordhoek J. Effect of vitamin E on the balance between pro- and antioxidant activity of ascorbic acid in microsomes from rat heart, kidney and liver. Toxicol Lett 1985;25:153–9.CrossRefPubMedGoogle Scholar
- Sterrenberg L, Julicher RHM, Goossens PAL, Bast A, Noordhoek J. Anthracycline-induced oxygen consumption and oxidative damage in rat liver microsomes are not necessarily coupled. A study with 8 structurally related anthracyclines. Free Radical Res Commun 1985;I:41–54.Google Scholar
- Van der Laarse A, Julicher RHM, Sterrenberg L, Bloys van Treslong CHF. Lipid peroxidation in neonatal rat heart cell cultures: effect of cumene hydroperoxide. Cardiovascular Res 1986;20:20–5.Google Scholar
- Julicher RHM, Sterrenberg L, Walenbergh LHP, Bast A, Noordhoek J. The effect of vitamin E-deficiency in isolated rat heart on the cellular defence system against free radicals during normal reperfusion after hypoxic, ischaemic and calcium-free perfusion. Free Radical Res Commun 1986;I:225–33.Google Scholar
- Julicher RHM, Sterrenberg L, Bast A, Riksen ROWMM, Koomen JM, Noordhoek J. The role of lipid peroxidation in the acute adriamycin-induced cardiotoxicity as studied in isolated rat heart. J Pharm Pharmacol 1986;38:277–82.PubMedGoogle Scholar
- Sterrenberg L, Julicher RHM, Goossens PAL, Bast A, Noordhoek J. Non-enzymic lipid peroxidation in microsomes and microsomal phospholipids induced by anthracyclines. Free Radical Res Commun 1986;I:369–78.Google Scholar
Copyright information
© Bohn, Scheltema & Holkema 1986