Effects of the pesticides thiotox, dichlorvos and carbofuran on the test fishMystus vittatus
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Abstract
A quantitative index of synergism, antagonism and additivity has been measured experimentally in the fishMystus vittatus for three pesticides viz. Thiotox (Endosulfan) (T), Dichlorvos (D) and Carbofuran (C). For a combination of two pesticides, the dose of the one pesticide of a pair was fixed at the no-effect level while the dose of the second pesticide was increased until the entire dose response curve was obtained. To evaluate interactions of three pesticides, the previous pair of pesticides was kept fixed at their combined TLO level, and the third pesticide was increased and again a dose-response curve was obtained. From the results obtained, it is shown that a particular combination could be synergistic, antagonistic or additive, depending on the relative doses employed. In the present study (T + D)/C combination was most synergistic (toxic) in nature while D/T and C/T were least toxic or antagonistic in their effects. However, T/D, (C + T)/D, C/D and D/C combinations were additive in nature. (D + T)/C, (D + C)/T, (T + C)/D and (C + D)/T combinations were found less synergistic in nature than (T + D)/C.
Keywords
Response Curve Dose Response Endosulfan Dose Response Curve CarbofuranPreview
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References
- Fabacher, D. L.: 1976,Bull. Environ. Contam. Toxicol. 16, 376.Google Scholar
- Koening, C. C.: 1975, The effects of DDT and mirex alone and in combination on the reproduction of a salt marsh Cyprinodont. FishAdinia xenica. Thesis, Florida State Univ., Tallahassee.Google Scholar
- Lech, J. J.: 1974,Biochem. Pharmacol. 23, 2403.Google Scholar
- Lech, J. J., Pepple, S. K. and Anderson, M.: 1973,Toxicol. Appl. Pharmacol. 25, 542.Google Scholar
- Macek, K. J.: 1975,Bull. Environ. Contam. Toxicol. 14, 648.Google Scholar
- Marking, L. L. and Mauck, W. L.: 1975,Bull. Environ. Contam. Toxicol. 13, 518.Google Scholar
- Mayer, F. L., Jr., Street, J. C., and Neuhold, J. M.: 1972,Toxicol. Appl. Pharmacol. 22, 347.Google Scholar
- Reinhold, K. A.: 1975,Dissertation Abs. 55, 75, 11545.Google Scholar
- Roales, R. R. and Perlmutter, A.: 1974,Bull. Environ. Contain. Toxicol. 12, 475.Google Scholar
- Schmidt, D. C. and Weber, L. J.: 1973,J. Fish. Res. Bd. Can. 30, 1310.Google Scholar
- Schubert, J., Riley, E. J., and Tyler, S. A.: 1978.J. Toxicol. Environ. Hlth. 4, 763.Google Scholar
- Statham, C. N. and Lech, J. J.: 1975,Toxicol. Appl. Pharmacol. 34, 83.Google Scholar
- Verma, S. R., Sarita Rani, Bansal, S. K. and Dalela, R. C.: 1979, Evaluation of comparative toxicity of thiotox, dichlorvos and carbofuran to two fresh water teleostsOphiocephalus punctatus andMystus vittatus. Environ. Pollut. (Comm.).Google Scholar