Chromatographia

, Volume 33, Issue 1–2, pp 19–24 | Cite as

Porous polymer packings from vinyl ether derivatives for reversed-phase liquid chromatography

  • C. Hirayama
  • H. Ihara
  • S. Nagaoka
  • H. Makise
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Summary

Spherical, porous-polymer particles for column packing in high-performance liquid chromatography were prepared by suspension copolymerization of alkylvinyl ether with triethyleneglycol divinyl ether. The hydrophobicity of the packings was easily adjusted by changing the monomer ratio. The packings showed the usual reversed-phase liquid chromatographic properties, but did not sho abnormal retention, tailing and broadening of peaks and irreversible adsorption of ionic and aromatic substances, owing to the lack of ionic or aromatic groups. In addition, the packings were stable in alkaline solutions because of the relative alkali stability of C−O−C bonds as compared with CO−O and Si−O−C bonds in conventional packings.

Key Words

Column liquid chromatography Porous polymer spherical packings Vinyl ether Alkali resistance No abnormal adsorption 
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References

  1. [1]
    R.K. Gilpin, M.F. Burke, Anal. Chem.45, 1383 (1973).CrossRefGoogle Scholar
  2. [2]
    N. Tanaka, Kagaku no Ryoiki37, 33 (1983).Google Scholar
  3. [3]
    K. Kimata, K. Iwaguchi, S. Onishi, K. Jinno, R. Eksteen, K. Hosoya, M. Araki, N. Tanaka, J. Chromatogr. Sci.27, 721 (1989).Google Scholar
  4. [4]
    Y. Ohtsu, Y. Shiojima, K. Koyama, K. Nakamura, O. Nakata, K. Noguchi, J. Chromatogr.481, 147 (1989).CrossRefGoogle Scholar
  5. [5]
    T. Ohtsu, Y. Tamura, M. Kasai, T. Uchida, Y. Yanagihara, K. Noguchi, J. Chromatogr.515, 175 (1990).CrossRefGoogle Scholar
  6. [6]
    H. Engelhardt, H. Löw, W. Eberhardt, M. Mauß, Chromatographia27, 535 (1989).CrossRefGoogle Scholar
  7. [7]
    N. Tanaka, K. Kimata, Y. Mikawa, K. Hosoya, T. Araki, J. Chromatogr.535, 13 (1990).CrossRefPubMedGoogle Scholar
  8. [8]
    R.L. Greyson, A.N. Patch, J. Chromatogr.242, 349 (1982).CrossRefGoogle Scholar
  9. [9]
    H.A. Mcleod, G. Larer, J. Chromatogr.244, 385 (1982).CrossRefGoogle Scholar
  10. [10]
    S.E. Tett, D.J. Cutler, K.F. Brown, J. Chromatogr. Biomed. Appl.344, 241 (1985).CrossRefGoogle Scholar
  11. [11]
    R.M. Smith, D.R. Garside, J. Chromatogr.407, 19 (1987).CrossRefGoogle Scholar
  12. [12]
    S. Coppi, A. Betti, C. Bighi, J. Chromatogr.442, 97 (1988).CrossRefGoogle Scholar
  13. [13]
    N. Tanaka, M. Araki, Advances in Chromatography30, 81 (1981).Google Scholar
  14. [14]
    N. Tanaka, T. Ebata, K. Hashizume, K. Hosoya, M. Araki, J. Chromatogr.475, 195 (1989).CrossRefGoogle Scholar
  15. [15]
    N. Tanaka, K. Hashizume, M. Araki, J. Chromatogr.400, 33 (1987).CrossRefGoogle Scholar
  16. [16]
    K. Yamsukawa, Y. Kimata, T. Uchida, K. Noguchi, J. Chromatogr.410, 129 (1987).CrossRefGoogle Scholar
  17. [17]
    N. Tanaka, K. Kimata, Y. Mikawa, K. Hosoya, T. Araki, J. Chromatogr.535, 13 (1990).CrossRefPubMedGoogle Scholar
  18. [18]
    G.A. Howard, A.J.P. Martin, Biochem. J.46, 532 (1950).Google Scholar
  19. [19]
    R.G. Baum, R. Saetre, EE Cantwell, Anal. Chem.52, 15 (1980).CrossRefGoogle Scholar
  20. [20]
    Y. Yanagihara, K. Noguchi, M. Honda, Jpn. Patent, 1–15822.Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1992

Authors and Affiliations

  • C. Hirayama
    • 1
  • H. Ihara
    • 1
  • S. Nagaoka
    • 1
  • H. Makise
    • 1
  1. 1.Department of Applied Chemistry, Faculty of EngineeringKumamoto UniversityKumamotoJapan

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