Pharmaceutisch Weekblad

, Volume 2, Issue 1, pp 266–270 | Cite as

Stability of corticosteroids under anaerobic conditions

II. 17-deoxy-21-dehydroprednisolone
  • D. Dekker
Original Articles


One of the identified decomposition products formed during the anaerobic decomposition of prednisolone, is 17-deoxy-21-dehydroprednisolone. This product can only be detected when the decomposition of prednisolone takes place at about pH = 6 or lower pH values.

The Chromatographic properties, the isolation and the structure elucidation of 17-deoxy-21-dehydroprednisolone are given.


Public Health Internal Medicine Corticosteroid Prednisolone Anaerobic Condition 
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Copyright information

© Bohn, Scheltema & Holkema 1980

Authors and Affiliations

  • D. Dekker
    • 1
  1. 1.Department of Analytical Pharmacy, Faculty of PharmacyState University of UtrechtGH UtrechtThe Netherlands

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