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Pharmaceutisch Weekblad

, Volume 2, Issue 1, pp 221–225 | Cite as

Xenobiotic-metabolizing enzymes in the fruitfly Drosophila melanogaster and the albino rat, with emphasis on glutathione S-transferase

  • A. J. Baars
Oorspronkelijke Artikelen
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Keywords

Public Health Internal Medicine Glutathione 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literatuur

  1. Gessner, T., A. Jacknowitz enC. A. Vollmer (1973)Biochem. J. 132, 249.Google Scholar
  2. Litterst, C. L., T. E. Gram, E. G. Mimnaugh, P. Leber, D. Emmerling enR. I. Freudenthal (1976)Drug Metab. Dispos. 4, 203.Google Scholar
  3. Mulder, G. J., enA. H. Hagedoorn (1974)Biochem. Pharmacol. 23, 2101.Google Scholar
  4. Baars, A. J., E. W. Van Dongen enD. D. Breimer (1977) Determination of thiol group compounds with DTNB: Some factors influencing colour development of reagent blanks and cysteine solutions,Pharm. Weekblad 112, 1117–1120.Google Scholar
  5. Baars, A. J., J. A. Zijlstra, E. Vogel enD. D. Breimer (1977) The occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity inDrosophila melanogaster microsomes, and the importance of this metabolizing capacity for the screening of carcinogenic and mutagenic properties of foreign compounds,Mutation Res. 44, 257–268.Google Scholar
  6. Baars, A. J., M. Jansen enD. D. Breimer (1978) The influence of phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin on glutathione S-transferase activity of rat liver cytosol,Biochem. Pharmacol. 27, 2487–2494.Google Scholar
  7. Baars, A. J., M. Jansen enD. D. Breimer (1979) Xenobiotic-metabolizing enzymes inDrosophila melanogaster. Epoxide hydratase and glutathione S-transferase activities, compared with similar activities in rat liver,Mutation Res. 62, 279–291.Google Scholar
  8. Baars, A. J., J. A. Zijlstra, M. Jansen, E. Vogel enD. D. Breimer (1979) Biotransformation and spectral interaction of xenobiotics with subcellular fractions fromDrosophila melanogaster, submitted for publication.Google Scholar
  9. Baars, A. J., S. Arnoldussen, D. C. Rauh enD. D. Breimer (1979) Developmental aspects of hepatic glutathione S-transferase activities in male rats, submitted for publication.Google Scholar

Copyright information

© Bohn, Scheltema & Holkema 1980

Authors and Affiliations

  • A. J. Baars
    • 1
  1. 1.Farmacologisch LaboratoriumSylvius Laboratoria der RijksuniversiteitRA Leiden

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