Veterinary Science Communications

, Volume 1, Issue 1, pp 243–250

New developments in muscle pathology: Nutritional myopathies including “muscular dystrophy” or “white muscle disease”

  • W. M. Allen
European Community Preview Article

Abstract

Dietary deficiencies of vitamin E and/or selenium may result in muscular degeneration in young calves and older growing animals. The preservation and storage of moist grain with propionic acid reduces its vitamin E content; feeding such grain to older animals may predispose them to the myodegeneration which often occurs following their return to spring grazing and unaccustomed exercise. Cold or wet windy weather may be another predisposing factor. Deficiency of vitamin E or selenium probably results in peroxidative damage to cell membranes which precedes tissue and muscular degeneration.

Kurzfassung

Vitamin E - und/oder Seleniummangel im Futter kann bei jungen Kälbern sowie bei älteren wachsenden Rindern eine Muskeldegeneration zur Folge haben. Die Konservierung und Speicherung von feuchtem Körnerfutter mit Propionsäure vermindert dessen Vitamin E-gehalt; Verfütterung an ältere Tiere könnte diese zu einer Myodegeneration, wie sie häufig im Frühjahr beim Eintrieb auf die neue Weide und zufolge der ungewohten Bewegung auftritt, prädisponieren. Schlechtes Wetter (Kälte, feucht und windig) könnte noch ein anderer prädisponierender Faktor sein. Vitamin E — oder Seleniummangel ist wahrscheinlich die Ursache einer peroxydativen Läsion der Zellmembran, welche einer Gewebs - und Musckeldegeneration vorausgeht.

Resume

Les carences alimentaires en vitamine E et/ou en sélénium peuvent entraîner une dégénérescence musculaire chez les veaux en bas âge, ainsi que chez les bovins plus âgés en cours de croissance. La conservation et le stockage de graines fourragères humides avec de l'acide propionique diminuent leur teneur en vitamine E; l'alimentation d'animaux plus âgés avec de telles graines pourrait les prédisposer à la dégénérescence musculaire qui se manifeste souvent au retour d'un pacage de printemps et à la suite de mouvements inhabituels. Les intempéries (froid, vent, humide) constitueraient un autre facteur prédisposant. Il paraît probable que la carence en vitamine E ou en sélénium provoque des lésions péroxydatives des membranes cellulaires, précurseurs de la dégénérescence tissulaire et musculaire.

Riassunto

Le carenze alimentari di vitamina E e/o di selenio possono dare origine a degenerazioni muscolari nei giovani vitelli, come pure bei bovini più grandi in via di crescita. La conservazione e l'accumulo di grani di foraggio umidi assieme all'acido propionico diminuiscono il loro contenuto in vitamina E; l'alimentazione di animali più anziani (adulti) con tali grani potrebbe predisporli alladegenerazione muscolare, che spesso si manifesta al ritorno al perscolo in primavera e in seguito a movimenti inabituati. Le intemperie (freddo, vento umido) costituirebbero un altro fattore predisponente. Sembra probabile che la carenza di vitamina E o di selenio provochi lesioni perossidative delle membrane cellulari, precursori della degenerazione tissulare e muscolare.

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Copyright information

© Elsevier Scientific Publishing Company 1977

Authors and Affiliations

  • W. M. Allen
    • 1
  1. 1.Agricultural Research CouncilInstitute for Research on Animal DiseasesNewburyUK

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