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Pterin metabolism in normal subjects and hyperphenylalaninaemic patients

Abstract

The application of high performance liquid chromatography to the estimation of urinary pterins is illustrated by results from normal subjects and from patients with phenylketonuria, dihydropteridine reductase deficiency and biopterin synthetase deficiency. In normal subjects following a phenylalanine load there is a temporary increase in pterin elimination, the pattern being different to that seen in chronic hyperphenylalaninaemia.

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References

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Dhondt, J.L., Farriaux, J.P., Largilliere, C. et al. Pterin metabolism in normal subjects and hyperphenylalaninaemic patients. J Inherit Metab Dis 4, 47–48 (1981). https://doi.org/10.1007/BF02263584

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Keywords

  • Public Health
  • Internal Medicine
  • Liquid Chromatography
  • High Performance Liquid Chromatography
  • Temporary Increase