The intermediates in the Hantzsch reaction of the methyl ester and diethylamide of phenylchloropyruvic acid with N,N′-diphenylthiourea are derivatives of 2-phenylimino-3,5-diphenyl-4-hydroxythiazoline-4-carboxylic acid. They exist as an equilibrium mixture of two diastereomers in solution.
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Mamedov, V.A., Nurkhametova, I.Z., Shagidullin, R.R. et al. Structure of intermediates in the Hantzsch reaction of phenylchloropyruvic acid derivatives with N,N′-diphenylthiourea. Chem Heterocycl Compd 35, 855–859 (1999). https://doi.org/10.1007/BF02252112
- Organic Chemistry
- Methyl Ester
- Acid Derivative