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Structure of intermediates in the Hantzsch reaction of phenylchloropyruvic acid derivatives with N,N′-diphenylthiourea

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Abstract

The intermediates in the Hantzsch reaction of the methyl ester and diethylamide of phenylchloropyruvic acid with N,N′-diphenylthiourea are derivatives of 2-phenylimino-3,5-diphenyl-4-hydroxythiazoline-4-carboxylic acid. They exist as an equilibrium mixture of two diastereomers in solution.

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Additional information

A. E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center, Russian Academy of Sciences, Kazan' 420088; Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 975–980, July, 1999.

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Mamedov, V.A., Nurkhametova, I.Z., Shagidullin, R.R. et al. Structure of intermediates in the Hantzsch reaction of phenylchloropyruvic acid derivatives with N,N′-diphenylthiourea. Chem Heterocycl Compd 35, 855–859 (1999). https://doi.org/10.1007/BF02252112

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Keywords

  • Methyl
  • Ester
  • Organic Chemistry
  • Methyl Ester
  • Acid Derivative