Chemistry of Heterocyclic Compounds

, Volume 35, Issue 12, pp 1441–1442 | Cite as

Synthesis of 3-cyano-3-ethoxycarbonyl-4-methyl-6-phenylpyridine-2(1H)-thione and its alkylation

  • S. G. Krivokolysko
  • V. D. Dyachenko
  • V. P. Litvinov
Article
Received:

Abstract

The condensation of acetaldehyde with cyanothioacetamide and ethyl benzoylacetate in the presence of N-methylmorpholine leads to the formation of 3-cyano-5-ethoxycarbonyl-4-methyl-6-phenylpyridine-2(1H)-thione. Alkylation of the last afforded the corresponding substituted 2-alkythiopyridines.

Keywords

Acetaldehyde Ethyl Organic Chemistry Alkylation Thione 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • S. G. Krivokolysko
  • V. D. Dyachenko
  • V. P. Litvinov

There are no affiliations available

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