Advertisement

Psychopharmacology

, Volume 116, Issue 4, pp 515–516 | Cite as

1,25 (OH)2 vitamin D3 levels in seasonal affective disorder: Effects of light

  • Dan A. Oren
  • Jay Schulkin
  • Norman E. Rosenthal
Article

Abstract

1,25 (OH)2 vitamin D3 levels were assessed in nine females and six males with winter seasonal affective disorder and in 15 age- and gender-matched controls in winter during periods with and without treatment with light therapy. No difference was found between groups or across conditions, though wide variations within each group make the presence of a type II error possible.

Key words

Vitamin D Blood Seasonal affective disorder Depression Winter 

References

  1. Adams JS, Clemens TL, Parrish JA, Holick MF (1982) Vitamin-D synthesis and metabolism after ultraviolet irradiation of normal and vitamin-D-deficient subjects. N Engl J Med 306:722–725Google Scholar
  2. Rosenthal NE, Sack DA, Gillin JC, Lewy AJ, Goodwin FK, Davenport Y, Mueller PS, Newsome DA, Wehr TA (1984) Seasonal affective disorder: a description of the syndrome and preliminary findings with light therapy. Arch Gen Psychiatry 41:72–80Google Scholar
  3. Sonnenberg J, Luine VN, Krey CR, Christakos S (1986) 1, 25-Dihydroxyvitamin D3 treatment results in increased choline acetyltransferase activity in specific brain nuclei. Endocrinology 118:1433–1439Google Scholar
  4. Stumpf WE (1988) Vitamin D — soltriol the heliogenic steroid hormone: somatotrophic activator and modulator. Histochemistry 89:209–219Google Scholar
  5. Stumpf WE, Privette TH (1989) Light, vitamin D and psychiatry. Psychopharmacology 97:285–294Google Scholar
  6. Terman M, Terman JS, Quitkin FM, McGrath PJ, Stewart JW, Rafferty B (1989) Light therapy for seasonal affective disorder: a review of efficacy. Neuropsychopharmacology 2:1–22Google Scholar
  7. Wehr TA, Skwerer RG, Jacobsen FM, Sack DA, Rosenthal NE (1987) Eye versus skin phototherapy of seasonal affective disorder. Am J Psychiatry 144:753–757Google Scholar

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Dan A. Oren
    • 1
  • Jay Schulkin
    • 1
  • Norman E. Rosenthal
    • 1
  1. 1.Clinical Psychobiology and Neuroendocrinology BranchesNational Institute of Mental HealthBethesdaUSA

Personalised recommendations