Early dyskinesia — vulnerability
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Abstract
Relative vulnerability to dyskinesia in terms of exposure to antipsychotic drugs prior to onset of dyskinesia was studied in a sample of 100 psychiatric patients with dyskinesia onset generally within a year or less of the point of study entry. Unipolar and bipolar patients were more vulnerable to dyskinesia than other diagnostic groups. In the total sample, lithium exposure did not appear to delay development of dyskinesia. Longer exposure to antiparkinson drugs was associated with delayed onset of dyskinesia. Past exposure to electroconvulsive therapy was related to decreased vulnerability to dyskinesia.
Key words
Tardive dyskinesia Antipsychotic drugs Schizophrenia Depression Bipolar disorderPreview
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References
- Casey DE (1984) Tardive dyskinesia and affective disorders. In: Gardos G, Casey DE (eds) Tardive dyskinesia and affective disorder. American Psychiatric Press, Washington, DC, pp 1–20Google Scholar
- Gardos G, Cole JO (1983) Tardive dyskinesia and anticholinergic drugs. Am J Psychiatry 140:200–202Google Scholar
- Gardos G, Cole JO, Rapkin R, LaBrie R, Bacquelod E, Moore P, Sovner R, Doyle J (1984) Anticholinergic challenge and neuroleptic withdrawal. Arch Gen Psychiatry 41:1030–1035Google Scholar
- Gardos G, Cole JO, Haskell D, Marby DW, Paine-Schniebolk S, Moore P (1988) The natural hystory of tardive dyskinesia. J Clin Psychopharmacology 8[4] suppl:31–37Google Scholar
- Guy W (1976) ECDEU Assessment Manual for Psychopharmacology. US Department of Health, Education and Welfare, Washington, DC, pp 534–537Google Scholar
- Jeste DV, Wyatt RJ (1982) Understanding and treating tardive dyskinesia. Gulford Press, New YorkGoogle Scholar
- Kane JM, Smith JM (1982) Tardive dyskinesia. Arch Gen Psychiatry 39:473–481Google Scholar
- Kane J, Woerner M, Weinhold P et al. (1982) A prospective study of tardive dyskinesia development: preliminary results. J Clin Psychopharmacol 2:345–349Google Scholar
- Kane JM, Woerner M, Borenstein M, Wegner J, Lieberman J (1986) Integrating incidence and prevalence of tardive dyskinesia. Psychopharmacol Bull 22:254–258Google Scholar
- Klawans H, Weiner W, Nauseida P (1977) The effect of lithium on an animal model of tardive dyskinesia. Prog Neuropsychopharmacol 1:53–60Google Scholar
- Mason AS, Granacher RP (1978) Clnical handbook of antipsychotic drug therapy. Brunner/Mazel, New YorkGoogle Scholar
- Schooler NR, Kane JM (1982) Research diagnoses for tardive dyskinesia. Arch Gen Psychiatry 39:486–487Google Scholar
- Simpson G, Varga E, Lee H, Zoubok B (1978) Tardive dyskinesia and psychotropic drug history. Psychopharmacology 58:117–124Google Scholar
- Toenniessen L, Casey D, McFarland B (1985) Tardive dyskinesia in the aged: duration of treatment relationships. Arch Gen Psychiatry 42:278–284Google Scholar
- Yassa R, Ghadrian A, Schwartz G (1983) Prevalence of tardive dyskinesia in affective disorder patients. J Clin Psychiatry 44:410–412Google Scholar
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