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Coexistence of spinal arteriovenous malformation and ankylosing spondylitis — Are they related?

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A 50-year-old man with long standing ankylosing spondylitis developed cauda equina syndrome, which was found to be coexistent with a spinal arterio-venous maliformation. Paraplegia ensued following an acute exacerbation of back pain along with an attack of uveitis. Vasculitis changes were found on resected abnormal vessels.

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  1. 1.

    Tucker, C.R., Fowles, R.E., Calin, A., Popp, R.L. Aoritis in ankylosing spondylitis: early detection of aortic root abnormalities with two dimensional echocardiography. Am J Med 1982, 49, 680–686.

  2. 2.

    Bulkley, B.H., Roberts, W.C. Ankylosing spondylitis and aortic regurgitation: description of the characteristic cardiovascular lesion from study of eight necropsy patients. Circulation 1973, 48, 1014–1027.

  3. 3.

    Roberts, W.C., Hollingsworth, J.F., Bulkley, B.H., Jaffe, R.B., Epstein, S.E., Stinson, E.B. Combined mitral and aortic regurgitation in ankylosing spondylitis: Angiographic and anatomic features. Am J Med 1974, 56, 237–243.

  4. 4.

    Kinsella, T.D., Johnson, L.G., Sutherland, R.I. Cardiovascular manifestations of ankylosing spondylitis. Can Med assoc J 1974, 3, 1309–1311.

  5. 5.

    Alves, M.G., Espirito-Santo, J., Queiroz, M.V., Madeira, H., Macieira-Coelho, E. Cardiac alterations in ankylosing spondylitis. Angiology 1988, 567–571.

  6. 6.

    Bergfeldt, L. HLA B27-associated rheumatic diseases with severe cardiac bradyarrhythmias: clinical features and prevalence in 223 men with permanent pacemakers. Am J Med 1983, 75, 210–215.

  7. 7.

    Bowie, E.A., Glasgow, G.L. Cauda equina lesions associated with ankylosing spondylitis: Report of three cases. Br Med J 1961, 2, 24–27.

  8. 8.

    Hauge, T. Chronic rheumatoid polyarthritis and spondylarthritis associated with neurological symptoms and signs occasionally simulating an intraspinal expansive process. Acta Chir Scand 1961, 120, 395–401.

  9. 9.

    Lee, M.L.H., Waters, D.J. Neurological complication of ankylosing spondylitis. Br Med J 1962, 1, 798.

  10. 10.

    Rosenkranz, W. Ankylosing spondylitis: cauda equina syndrome with multiple spinal arachnoid cysts. J Neurosurg 1973, 34, 241–243.

  11. 11.

    Gordon, A.L., Yudell, A. Cauda equina lesions associated with rheumatoid spondylitis. Ann Intern Med 1973, 78, 555–557.

  12. 12.

    Young, A., Dixon, A., Getty, J., Renton, P., Vacher, H. Cauda equina syndrome complicating ankylosing spondylitis: use of electromyography and computerised tomography in diagnosis (case report). Ann Rheum Dis 1981, 40, 317–322.

  13. 13.

    Bartleson, J.D., Cohen, M.D., Harrington, T.M., Goldstein, N.P., Ginsburg, W.W. Cauda equina syndrome secondary to long-standing ankylosing spondylitis. Ann Neurol 1983, 14, 662–668.

  14. 14.

    Tullous, M.W., Skerhut, H.E.I., Story, J.L., et al. Cauda equina syndrome of long standing ankylosing spondylitis- case report and review of literature. J Neurosurg 1990, 73, 441–447.

  15. 15.

    Kramer, L.D., Krouth, G.J. Computerized tomography: an adjunct to early diagnosis in the cauda equina syndrome of ankylosing spondylitis. Arch Neurol 1978, 35, 116–118.

  16. 16.

    Abello, R., Rovira, M., Sanz, M.P., et al. MRI and CT of ankylosing spondylitis with vertebral scalloping. Neuroradiology 1988, 30, 272–275.

  17. 17.

    Chang, T.W., Huang, K.M., Chen, R.C. Clinical manifestations of 9 patients with spinal arteriovenous malformations. Chinese Med J (Taipei) 1988, 42, 469–474.

  18. 18.

    Criscuolo, G.R., Long, D.M. Vascular anomalies of the spinal cord. In: The Adult Spine: Principles and Practice. Ed-in-chief: Frymoyer, J.W., New York, Raven Press Ltd, 1991, 679–695.

  19. 19.

    Linssen, W.H.J.P., Jansen, A.P.H., Gabreels, F.J.M., et al. Spinal angioma: The meaning of cerebrospinal fluid lactic acid in the etiology and differential diagnosis of transverse myelopathy. Clin Neurol Neurosurg 1990, 92–2, 131–136.

  20. 20.

    Shephard, R.H. Spinal arteriovenous malformations and subarachnoid hemorrhage. Br J Neurosurg 1992, 6, 5–12.

  21. 21.

    Haddad, F.S., Sachdev, J.S., Bellapravalu, M. Neuropathic bladder in ankylosing spondylitis with spinal diverticula. Urology 1990, 35, 313–316.

  22. 22.

    Hassan, I. Cauda equina syndrome in ankylosing spondylitis: Report of six cases. J Neurol Neurosurg Psychiatry 1976, 39, 1172–1178.

  23. 23.

    Peeters, A.J., Van den Wall Bake, A.W., Daha, M.R., Breedveld, F.C. Inflammatory bowel disease and ankylosing spondylitis associated with cutaneous vasculitis, glomerulonephritis, and circulating immune complexes. Ann Rheum Dis 1990, 49, 638–640.

  24. 24.

    Beauvais, C., Kaplan, G., Mougenot, B., Michel, C., Marinho, E. Cutaneous vasculitis and Ig A glomerulonephritis in ankylosing spondylitis. Ann Rheum Dis 1993, 52, 61–62.

  25. 25.

    Shaw, P.J., Allcutt, D.A., Bates, D., Crawford, P.J. Cauda equina syndrome associated with multiple lumbar arachnoid cysts in ankylosing spondylitis: improvement following surgical therapy. J Neurol Neurosurg Psychiatry 1990, 53, 1076–1079.

  26. 26.

    Confavreux, C., Larbre, J.P., Lejeune, E., et al. Cerebrospinal fluid dynamics in the tardive cauda equina syndrome of ankylosing spondylitis. Ann Neurol. 1991, 29, 221–223.

  27. 27.

    Okada, S., Hase, H., Hieasawa, Y., et al. A case report of lumboperitoneal shunt for cauda equina syndrome in ankylosing spondylitis. Spine 1992, 35, s59-s61.

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Correspondence to Dr. J. Y. Chen.

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Chen, J.Y., Ho, H.H., Jan Wu, Y.J. et al. Coexistence of spinal arteriovenous malformation and ankylosing spondylitis — Are they related?. Clin Rheumatol 13, 533–536 (1994).

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Key words

  • Ankylosing Spondylitis
  • Spinal Arteriovenous Malformation
  • Vasculitis
  • Cauda Equina Syndrome