The American Journal of Digestive Diseases

, Volume 14, Issue 9, pp 643–651 | Cite as

Fatal Strongyloidiasis following corticosteroid therapy

  • Francisco Civantos
  • Morton J. Robinson


Two fatal strongyloides stercoralis infections found at autopsy in patients who had received corticosteroid therapy are presented. A successfully treated case of strongyloidiasis with pulmonary infiltration is also reported. Difficulties in diagnosis, usefulness of upper jejunal intubation, and the importance of ruling out strongyloidiasis prior to administration of corticosteroids to patients with eosinophilia, particularly Vietnam veterans, are discussed.


Public Health Corticosteroid Eosinophilia Corticosteroid Therapy Vietnam Veteran 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Craig and Faust's Clinical Parasitology (ed. 7), Faust, E. and Russel, P., Eds. Lea, Philadelphia, 1964, Chap. 19.Google Scholar
  2. 2.
    Yoeli, M., Most, H., Berman, H., andTesse, B. The problem of strongyloidism among the mentally retarded in institutions.Trans Roy Soc Trop Med Hyg 57:336, 1963.CrossRefPubMedGoogle Scholar
  3. 3.
    Napier, L. Strongyloides stercoralis infection. II. Strongyloidiasis among ex-prisoners-of-war.J Trop Med Hyg 52:46, 1949.Google Scholar
  4. 4.
    Cruz, T., Reboucas, G., andRocha, H. Fatal strongyloidiasis in patients receiving corticosteroids.New Eng J Med 275:1093, 1966.PubMedGoogle Scholar
  5. 5.
    Yoeli, M., Most, H., Berman, H., andScheinesson, G. The clinical picture and pathology of massive strongyloides infection in a child.Trans Roy Soc Trop Med Hyg 57:346, 1963.CrossRefPubMedGoogle Scholar
  6. 6.
    Hartz, P. Human strongyloidiasis with internal autoinfection.Arch Path (Chicago) 41:601, 1946.Google Scholar
  7. 7.
    Swartzwelder, J., Frye, W., Muhleisen, J., Miller, J., Lamert, R., Pena Chavarria, A., Abadie, S., andAnthony, S. Diathiazanine, an effective broad-spectrum anthelmintic.JAMA 165:2063, 1957.Google Scholar
  8. 8.
    Stemmermann, G. N., andNakasone, N. Strongyloides stercoralis infestation. Malabsorption defect with reaction to dithiazanine iodide.JAMA 174:1250, 1960.Google Scholar
  9. 9.
    Most, H., Yoeli, M., Campbell, W., andCuckler, A. The treatment of strongyloides and enterobius infections with thiabendazole.Amer J Trop Med 14:379, 1965.PubMedGoogle Scholar
  10. 10.
    Amir-Ahmadi, H., Braun, P., Neva, F. A., Gottlieb, L. S., andZamcheck, N. Strongyloidiasis at the Boston City Hospital. Emphasis on gastrointestinal pathophysiology and successful therapy with thiabendazole.Amer J Dig Dis 13:959, 1968.CrossRefPubMedGoogle Scholar
  11. 11.
    Jones, C. Clinical studies in human strongyloidiasis. I. Semeiology.Gastroenterology 16:743, 1950.PubMedGoogle Scholar
  12. 12.
    Thompson, J. Special Topics “check sample” No. ST-28, March 1967, Council on Continuing Education, American Society of Clinical Pathologists, 1967.Google Scholar
  13. 13.
    Hudson, G. The marrow reserve of eosinophils. Effect of cortical hormones on the foreign protein response.Brit J Haemat 10:122, 1964.PubMedGoogle Scholar
  14. 14.
    Dustin, P., Jr. Cortisone et stathmocineses; à propos de récherches sur l'éosinopénie hormonale.Sang (Paris) 28:581, 1957.Google Scholar
  15. 15.
    Brown, H., andPerna, V. An overwhelming strongyloides infection.JAMA 168:1648, 1958.Google Scholar
  16. 16.
    Kyle, L., McKay, D., andSparling, H. Strongyloidiasis.Ann Intern Med 29:1014, 1948.Google Scholar

Copyright information

© Hoeber Medical Division • Harper & Row 1969

Authors and Affiliations

  • Francisco Civantos
    • 2
    • 1
  • Morton J. Robinson
    • 2
  1. 1.the University of Miami School of MedicineUSA
  2. 2.Department of PathologyMount Sinai HospitalMiami Beach

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