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The study of the biphasic curve of gastric secretion following insulin stimulation

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Insulin was administered intravenously to 5 unanesthetized pigtail monkeys with isolated, vagally innervated, gastric pouches, and to 5 with Heidenhain pouches. Analysis of 45 tests demonstrated an obvious increase of gastric acid during the first 2 hr. in the group with vagally innervated pouches. Reliable evidence of the second or late phase of gastric secretion was not found.

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This research was supported by the Dachler Grant, U.S.P.H.S. Grants A-2187 and APD-11,693, and Initiative 171 Funds, State of Washington.

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Cammock, E.E., Nyhus, L.M. & Harkins, H.N. The study of the biphasic curve of gastric secretion following insulin stimulation. Digest Dis Sci 8, 337–343 (1963). https://doi.org/10.1007/BF02237706

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  • Public Health
  • Gastric Acid
  • Late Phase
  • Gastric Secretion
  • Gastric Pouch