The American Journal of Digestive Diseases

, Volume 12, Issue 9, pp 916–922 | Cite as

Ascites in cirrhosis

Relative importance of portal hypertension and hypoalbuminemia
  • Donald O. Castell


The relation of wedged hepatic vein pressure and serum albumin concentrations to ascites in 20 patients with cirrhosis of the liver has been studied. Evaluation of the data reveals a much stronger relation of the presence of ascites to serum albumin levels than to the hepatic wedge pressure. Application of the same analytic methods to a previous report on a larger group of cirrhotic patients reveals similar findings.

The results suggest that hypoalbuminemia is of much greater importance than portal hypertension in the pathogenesis of ascites in patients with cirrhosis of the liver.


Public Health Hypertension Albumin Serum Albumin Portal Hypertension 
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Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1967

Authors and Affiliations

  • Donald O. Castell
    • 1
  1. 1.From the Internal Medicine ServiceU. S. Naval HospitalGreat Lakes

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