The American Journal of Digestive Diseases

, Volume 16, Issue 11, pp 1014–1018

Hepatitis, arthritis and lupus cell phenomena caused by methyldopa

  • Michael Eliastam
  • A. W. Holmes
Case Report

DOI: 10.1007/BF02235014

Cite this article as:
Eliastam, M. & Holmes, A.W. Digest Dis Sci (1971) 16: 1014. doi:10.1007/BF02235014


A patient is described who developed hepatocellular jaundice after methyldopa was administered. When the drug was again prescribed, hepatitis recurred. This exacerbation, along with transient arthritis, antinuclear antibodies and positive LE cell tests, document this as a case of hepatotoxicity due to methyldopa.

Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1971

Authors and Affiliations

  • Michael Eliastam
    • 1
  • A. W. Holmes
    • 1
  1. 1.From the Section of Hepatology, Department of MedicineRush-Presbyterian-St. Luke's Medical CenterChicago

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