Diseases of the Colon & Rectum

, Volume 44, Issue 2, pp 284–287 | Cite as

Adenocarcinoma at a strictureplasty site in Crohn's disease

Report of a case
  • Nora T. Jaskowiak
  • Fabrizio Michelassi
Case Reports


Strictureplasties have proven useful and safe in Crohn's disease. Concerns have been raised, however, about the potential of carcinoma arising at the strictureplasty site. Here the authors report a case of a small-bowel adenocarcinoma developing at the site of a prior strictureplasty in a middle-aged male patient seven years postoperatively in the absence of any other preneoplastic disease of the small bowel. Presenting symptoms were of progressive obstruction after a long period of quiescent disease. With this report comes stronger evidence that adenocarcinoma does occur at strictureplasty sites, raising questions of its long-term safety.

Key words

Crohn's disease Strictureplasty Small-bowel adenocarcinoma 


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  1. 1.
    Dalziel TK. Chronic interstitial enteritis. BMJ 1913;2:1068–70.Google Scholar
  2. 2.
    Crohn BB, Ginzburg L, Oppenheimer GO. Regional ileitis: a pathologic and clinical entity. JAMA 1932;99:1323–9.Google Scholar
  3. 3.
    Ginzburg L, Schneider KM, Dreizin DH, Levinson C. Carcinoma of the jejunum occurring in a case of regional enteritis. Surgery 1956;39:347–51.PubMedGoogle Scholar
  4. 4.
    Marchetti F, Fazio VW, Ozuner G. Adenocarcinoma arising from a strictureplasty site in Crohn's disease: report of a case. Dis Colon Rectum 1996;39:1315–21.CrossRefPubMedGoogle Scholar
  5. 5.
    Michelassi F, Testa G, Pomidor WJ, Lashner BA, Block GE. Adenocarcinoma complicating Crohn's disease. Dis Colon Rectum 1993;36:654–61.PubMedGoogle Scholar
  6. 6.
    Collier PE, Turowski P, Diamond DL. Small intestinal adenocarcinoma complicating regional enteritis. Cancer 1985;55:516–21.PubMedGoogle Scholar
  7. 7.
    Lee EC, Papaioannou N. Minimal surgery for chronic obstruction in patients with extensive or universal Crohn's disease. Ann R Coll Surg Engl 1982;64:229–33.PubMedGoogle Scholar
  8. 8.
    Alexander-Williams J, Haynes IG. Conservative operations for Crohn's disease of the small bowel. World J Surg 1985;9:945–51.CrossRefPubMedGoogle Scholar
  9. 9.
    Tjandra JJ, Fazio VW. Strictureplasty without concomitant resection for small bowel obstruction in Crohn's disease. Br J Surg 1994;81:561–3.PubMedGoogle Scholar
  10. 10.
    Ozuner G, Fazio VW, Lavery IC, Church JM, Hull TL. How safe is strictureplasty in the management of Crohn's disease? Am J Surg 1996;171:57–61.CrossRefPubMedGoogle Scholar
  11. 11.
    Swinson CM, Slavin G, Coles EC, Booth CC. Coeliac disease and malignancy. Lancet 1983;1:111–5.CrossRefPubMedGoogle Scholar

Copyright information

© The American Society of Colon and Rectal Surgeons 2001

Authors and Affiliations

  • Nora T. Jaskowiak
    • 1
  • Fabrizio Michelassi
    • 1
  1. 1.Department of SurgeryThe University of ChicagoChicago

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