Summary and conclusions
In a study of gastric freezing in 188 outpatients, placebo response was as good as response to the the treatment itself, nor were results improved by addition of a modified and simplified postfreeze medical program.
Although gastric freezing does seem to have a desirable physiologic effect on ulcer patients with respect to pain relief and transient depression of gastric acidity, in our expeirence these effects are too brief to be therapeutically useful.
Attempts to prolong such desirable secretory alterations by the use of anticholinergic drugs and antacids were unsuccessful.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Perry, G. T., Dunphy, J. V., Fruin, R. C. andLittman, A. Gastric freezing for duodenal ulcer—a double blind study.Gastroenterology 47:6, 1964.
Rose, H., Fordtran, J. S., Harrell, R., andFriedman, B. A controlled study of gastric freezing for the treatment of duodenal ulcer.Gastroenterology 47:10, 1964.
Karacadag, S., andKlotz, A. P. Gastric “freezing” in peptic ulcer.Ann. Int. Med. 61: 645, 1964.
Karacadag, S., andKlotz, A. P. A physiologic Interpretation of gastric freezing in the human.Am. J. Dig. Dis. 9:319, 1964.
Klotz, A. P., andChristodoulopoulos, J. B. The secretory physiology of gastric freezing.Am. J. Dig. Dis. 10:31, 1965.
Wangensteen, O. H., Peter, E. T., Nicoloff, D. M., Sosin, H., andBernstein, E. F. Achieving “physiological gastrectomy” by gastric freezing.J.A.M.A. 180:439, 1962.
Owens, F. J., Brown, C. H., Sullivan, B. H., andTretbar, L. L. Clinical experiences in gastric freezing for peptic ulcer.Clevel and Clin. Quart. 31:1, 1964.
McHardy, G., Atik, M., Balart, L., Sekinger, D., McHardy, R., Cradic, H., Roberson, F., andJudice, R. An evaluation of gastric hypothermia.Am. J. Dig. Dis. 9:717, 1964.
Karacadag, S., andKlotz, A. P. Side effects and complications of gastric freezing.JAMA. 188:1151, 1964.
Karacadag, S., andKlotz, A. P. Multiple gastric freezing.Am. J. Dig. Dis. 10:116, 1965.
Fellow in Gastroenterology.
About this article
Cite this article
Lubos, M.C., Viril, L.C. & Klotz, A.P. A controlled study of outpatient gastric freezing. Digest Dis Sci 11, 266–271 (1966). https://doi.org/10.1007/BF02233973
- Public Health
- Pain Relief