The American Journal of Digestive Diseases

, Volume 11, Issue 8, pp 630–647 | Cite as

The malignant carcinoid syndrome

Report of 5 cases
  • Raimonds J. Gailitis
Article

Keywords

Public Health Carcinoid Syndrome Malignant Carcinoid Malignant Carcinoid Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    William, E. D., andSandler, M. The classification of carcinoid tumors.Lancet 1:238, 1963.PubMedGoogle Scholar
  2. 2.
    Peart, W. S., Porter, K. A., Robertson, J. I. S., Sandler, M., and Baldock, E. Carcinoid syndrome due to pancreatic duct neoplasm secreting 5- hydroxytryptophan and 5-hydroxytryptamine.Lancet 1: 239, 1963.PubMedGoogle Scholar
  3. 3.
    Williams, E., andAzzopardi, J. G. Tumors of the lung and the carcinoid syndrome.Thorax 15:30, 1960.PubMedGoogle Scholar
  4. 4.
    Frank, H. D., andLieberthal, M. M. Carcinoid syndrome originating in bronchial adenoma.Arch Intern Med 111:791, 1963.PubMedGoogle Scholar
  5. 5.
    Gailitis, R. J., andSchreiber, W. Malignant carcinoid syndrome and latest concepts in serotonin metabolism. Use of cortisone, prednisone, and antiserotonin compound 45–50.Amer J Surg 99:84, 1960.PubMedGoogle Scholar
  6. 6.
    Green, D., Joynt, R. J., andVan Allen, M. W. Neuromyopathy associated with a malignant carcinoid tumor.Arch Intern Med 114:494, 1964.PubMedGoogle Scholar
  7. 7.
    Oates, J. A., Melmon, K., Sjoerdsma, A., Gillespie, L., andMason, D. T. Release of kinine peptide in the carcinoid syndrome.Lancet 1:514, 1964.Google Scholar
  8. 8.
    Mengel, C. E. Cutaneous manifestations of the malignant carcinoid syndrome: Severe pruritus and orange blotches.Ann Intern Med. 6:989, 1963.Google Scholar
  9. 9.
    Demis, D. J., andZimmer, J. G. Histaminuria and mastocytosis.Arch Intern Med 111:309, 1963.Google Scholar
  10. 10.
    Mutter, R. D., Tannenbau, M., andUltmann, J. E. Systemic mast cell disease.Ann Int Med 59: 887, 1963.PubMedGoogle Scholar
  11. 11.
    Warner, R. R. Hyperserotoninemia in functional gastrointestinal disease.Ann Intern Med 39:464, 1963.Google Scholar
  12. 12.
    Davidson, J., Sjoerdsma, A., Loomis, L. N., and Udenfriend, S. Studies with the serotonin precursor, 5-hydroxytryptophan in experimental animals and man.J Clin Invest 36: 1594, 1957.PubMedGoogle Scholar
  13. 13.
    Page, I. H., andMcCubbin, G. W. Serotonin or tenure, for the pharmacologist.Circulation 16:161, 1956.Google Scholar
  14. 14.
    Sothren, A. L. Functioning metastatic bronchial carcinoid with elevated levels of serum and cerebrospinal fluid serotonin and pituitary adenoma.J Clin Endocr 20: 298, 1960.PubMedGoogle Scholar
  15. 15.
    Schenkloth, R., Page, I. H., Del Greco, F., andCorcoran, A. C. Effects of serotonin antagonists in normal subjects and in patients with carcinoid tumors.Circulation 16:523, 1957.PubMedGoogle Scholar
  16. 16.
    Peart, W. S., Andrews, T. M., andRobertson, J. I. S. Serotonin release induced with intravenous adrenalin or noradrenalin.Lancet 1:577, 1961.PubMedGoogle Scholar
  17. 17.
    Levine, R. J., Sjoerdsma, A. Pressoramines and the carcinoid flush.Ann Intern Med 5: 818, 1963.Google Scholar
  18. 18.
    Hollands, W., Michelson, A. S., andWilkins, R. N. Serotonin and antiserotonins. 1. Their circulatory, respiratory and renal effects in man.Circulation 16: 246, 1957.PubMedGoogle Scholar
  19. 19.
    Haverbeck, B. J., Hogben, C. A. H., Moran, N. C, andTerry, L. L. Effect of serotonin (5-hydroxytryptamine) and related compounds on gastric secretion and intestinal motility in dogs.Gastroenterology 32: 1058, 1957.PubMedGoogle Scholar
  20. 20.
    Erspamer, V. Serotonin (5-hydrotryptamine).Physiol Rev. 6:425, 1954.Google Scholar
  21. 21.
    Erspamer, V. Pharmacology of indolealchylamines.Pharmacol Rev 6:425, 1954.PubMedGoogle Scholar
  22. 22.
    MacDonald, R. A. Study of 356 carcinoids of the gastrointestinal tract.Am J Med 21:867, 1956.PubMedGoogle Scholar
  23. 23.
    Hendrix, T. R., Atkinson, M., Clifton, J. A., andIngelfinger, F. G. The effect of 5-hydroxytryptamine on intestinal motor function in man.Amer J Med 23:886, 1957.PubMedGoogle Scholar
  24. 24.
    Vilkins, R. N., andHollander, W. Serotonin and antiserotonin. H. Clinical studies especially in essential hypertension with benzyl analog of serotonin (b.a.s.).Circulation 16:256, 1957.PubMedGoogle Scholar
  25. 25.
    Heilmeyer, L., Kuehn, H. A., Clottten, R., andLipp, A. Metastasierendes Duenndarm-carcinoid.Deutsch Med Wschr 81:501, 1956.PubMedGoogle Scholar
  26. 26.
    Fein, S. B., andKnidson, K. P. The malignant carcinoid syndrome; a case report with biochemical studies.Cancer 9:148, 1956.PubMedGoogle Scholar
  27. 27.
    McElroy, W. D., and Glass, H. B. (Eds.). “The 5-hydroxyindole Pathway of Tryptophane Metabolism.” In A Symposium on Amino Acid Metabolism. Johns Hopkins Press, Baltimore, 1955.Google Scholar
  28. 28.
    Jenkins, G. S., andButcher, P. G. A. Malignant argentaffinoma with cyanosis and pulmonary stenosis.Lancet 26:331, 1955.Google Scholar
  29. 29.
    Pharm, J. B., Fahim, I., Sullivan, F. M., andRobinson, J. M. Possible role of 5-hydroxytryptamine in toxemia of pregnancy.Lancet 2:553, 1963.Google Scholar
  30. 30.
    Eschbach, J. W., Rinaldo, J. A. Jr. Metastatic carcinoid: a familiar occurrence.Ann Intern Med 57:647, 1962.Google Scholar
  31. 31.
    Urales, L., Murray, M., Wolf, R. Results of pharmacologic treatment in malignant carcinoid syndrome.New Engl J Med 267:435, 1963.Google Scholar
  32. 32.
    Reed, M. L. et al. Treatment of disseminated carcinoid tumors including hepatic artery catheterization.New Engl J Med 269:1005, 1963.PubMedGoogle Scholar

Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1966

Authors and Affiliations

  • Raimonds J. Gailitis
    • 1
  1. 1.From the Medical Departments of Grant Hospital and Research and Educational HospitalsUniversity of IllinoisChicago

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