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The American Journal of Digestive Diseases

, Volume 13, Issue 7, pp 608–614 | Cite as

Anticholinergic drug action on pancreatic exocrine outflow in man and dog

  • H. Schapiro
  • L. D. Wruble
  • J. W. Estes
  • R. Sherman
  • L. G. Britt
Article

Summary

The endogenous secretin mechanism in dogs and in man is very sensitive to low concentrations of anticholinergic drugs. The release of secretin may be blocked by very small doses of these anticholinergic drugs, but once secretin gets into the bloodstream, its action can only be partially blocked by very large concentrations of the anticholinergic drugs.

Keywords

Public Health Drug Action Small Dose Secretin Large Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1968

Authors and Affiliations

  • H. Schapiro
    • 1
  • L. D. Wruble
    • 1
  • J. W. Estes
    • 1
  • R. Sherman
    • 1
  • L. G. Britt
    • 1
  1. 1.From the Department of Anatomy, College of Basic Medical Sciences and Departments of Medicine (Division of Gastroenterology) and SurgeryUniversity of Tennessee Medical UnitsMemphis

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