The American Journal of Digestive Diseases

, Volume 17, Issue 7, pp 583–590 | Cite as

Histologic and functional alterations of human exocrine pancreas in Manson's schistosomiasis

  • Carlos B. Mott
  • Dirceu P. Neves
  • Masayuri Okumura
  • Thales De Brito
  • Agostinho Bettarello


The exocrine pancreas of 20 patients with the hepatosplenic form of Manson's schistosomiasis and portal hypertension was examined. Surgical biopsies taken from the tail of the pancreatic gland during splenectomy and splenorenal shunts were examined histologically. Studied by the secretin test, peak bicarbonate concentrations in 16 of the 20 patients were below the lower critical statistical level; in 14 patients, marked histopathologic changes were found in the exocrine pancreas.


Hypertension Bicarbonate Statistical Level Portal Hypertension Secretin 
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Copyright information

© Harper & Row, Publishers 1972

Authors and Affiliations

  • Carlos B. Mott
    • 1
  • Dirceu P. Neves
    • 1
  • Masayuri Okumura
    • 1
  • Thales De Brito
    • 1
  • Agostinho Bettarello
    • 1
  1. 1.From the Department of Internal Medicine (Division of Gastroenterology), Faculty of MedicineUniversity of São PauloBrazil

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