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Clinical Rheumatology

, Volume 15, Issue 1, pp 62–66 | Cite as

Multicentric reticulohistiocytosis

  • H. Kocanaogullari
  • H. Ozsan
  • F. Oksel
  • G. Ozturk
  • G. Kandiloglu
  • E. E. Ustun
  • E. Doganavsargil
Case Report

Summary

We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis; however, biopsies from the nodules on the oral mucosa and ear revealed multicentric reticulohistiocytosis. The large nodule over the olecranon process, simulating a rheumatoid nodule but diagnosed as multicentric reticulohistiocytosis with biopsy; ulcerated and haemorrhagic nodules on the oral mucosa; and rapidly progressive joint destructions make our case interesting.

Key words

Multicentric Reticulohistiocytosis Destructive Polyarthritis Mucocutaneous Eruption Azathioprine 

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References

  1. 1.
    Ginsburg, W.W., O'Duffy, J.D. Multicentric reticulohistiocytosis. In: Textbook of Rheumatology. 4th ed., Eds.: Kelley, W.N. et al. Philadelphia, WB Saunders 1993, 1444–1448.Google Scholar
  2. 2.
    Lesher, J.L., Allen, B.S. Multicentric reticulohistiocytosis. J Am Acad Dermatol 1984, 11, 312–323.Google Scholar
  3. 3.
    Weisman, M.H. Arthritis associated with hematologic disorders, storage diseases, disorders of lipid metabolism, and dysproteinemias. In: Arthritis and Allied Conditions 12th ed., Eds.: Mc Carty, D.J., and Koopman, W.J., Philadelphia, Lea-Febiger 1993, 1457–1482.Google Scholar
  4. 4.
    Valente, M., Parenti, A., Cipriani, R., Peserico, A. Familial histiocytic dermatoarthritis. Histologic and ultrastuctural findings in two cases. Am J Dermatopathol 1987, 9, 491–496.PubMedGoogle Scholar
  5. 5.
    Amor, B., Kahan, A., Laoussadi, B., Mariette, X. Multicentric reticulohistiocytosis. A case with unusual clinical, radiologic and ultrastructural aspects. Rev Rheum Mal Osteoartic 1987, 54, 113–119.Google Scholar
  6. 6.
    Fiumicelli, A., Bruni, L. Multicentric reticulohistiocytosis (lipoid dermato-arthritis). A radiologic study of 3 cases. Radiol Med 1990, 80, 278–285.Google Scholar
  7. 7.
    Kesaniemi, Y.A., Ehnholm, C., Miettinen, T.A. Multicentric reticulohistiocytosis another lipid disorder with normolipidemic xathomatosis? Atheroscleosis 1987, 68, 179–189.CrossRefGoogle Scholar
  8. 8.
    Nakajima, Y., Sato, K., Morika, H., Torikal, S., Hidano, A., Nishioka, K., Kashiwazaki, S. Severe progressive erosive arthritis in multicentic reticulohistiocytosis: possible involvement of cytokines in synovial proliferation. J Rheumatol 1992, 19, 1643–1646.PubMedGoogle Scholar
  9. 9.
    Lambert, C.M., Nuki, G. Multicentric reticulohistiocytosis with arthritis and cardiac infiltration: regression following treatment underlying malignancy. Ann Rheum Dis 1992, 51, 815–817.PubMedGoogle Scholar
  10. 10.
    Janssen, B.A., Kencian, J., Brooks, P.M. Close temporal and anatomic relationship between multicentric reticulohistiocytosis and carcinoma of the breast. J Rheumatol 1992, 19, 322–324.PubMedGoogle Scholar
  11. 11.
    Carey, R.N., Blotzer, J.W., Wolfe, I.D., Glusman, S.M., Arnett, F.C. Multicentric reticulohistiocytosis and Sjögren's syndrome. J Rheumatol 1985, 12, 1193–1195.PubMedGoogle Scholar
  12. 12.
    Ginsburg, W.W., O'Duffy, J.D., Morris, J.L., Huston, K.A. Multicentric reticulohistiocytosis: response to alkylating agents in six patients. Ann Intern Med 1989, 115, 384–388.Google Scholar
  13. 13.
    Conaghan, P., Miller, M., Dowling, J.P., Cowen, P., Littlejohn, G. A unique presentation of multicentric reticulohistiocytosis in pregnancy. Arthritis Rheum 1993, 36, 269–272.PubMedGoogle Scholar
  14. 14.
    Gourmelen, O., Le Loet, X., Fortier-Beaulieu, M., Thomine, E., Ledan, G., Lauret, P., Deshayes, P. Methotrexate treatment of multicentric reticulohistiocytosis. J Rheumatol 1991, 18, 627–628.PubMedGoogle Scholar
  15. 15.
    Guillen, C., Fortea, J.M., Serrano, G., Martorell, M.A., Cogollos, E., Alegre, V., Aliaga, A. Multicentric reticulohistiocytosis. Dermatologica 1984, 169, 311–317.PubMedGoogle Scholar

Copyright information

© Clinical Rheumatology 1996

Authors and Affiliations

  • H. Kocanaogullari
    • 1
  • H. Ozsan
  • F. Oksel
    • 1
  • G. Ozturk
    • 3
  • G. Kandiloglu
    • 2
  • E. E. Ustun
    • 4
  • E. Doganavsargil
    • 1
  1. 1.Division of Rheumatology, Department of MedicineEge UniversityBornova, IzmirTurkey
  2. 2.the Department of MedicineDivision of Pathology of the Ege University, School of MedicineIzmirTurkey
  3. 3.the Department of MedicineDivision of Dermatology of the Ege University, School of MedicineIzmirTurkey
  4. 4.the Department of MedicineDivision of Radiology of the Ege University, School of MedicineIzmirTurkey

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