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Therapeutic principles in management of peptic ulcer

4. Radiation therapy with Cobalt-60

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1. Cobalt-60 teletherapy has been given to 72 patients with complicated peptic ulcer as a supplement to medical treatment.

2. The therapy was well tolerated with minimal reaction.

3. The treatment usually decreased the Histalog-stimulated and basal gastric acid secretion. There was a gradual return of hyperacidity in some patients in 6 to 12 months.

4. The initial symptomatic and roentgen response has been good in all patients. There was recurrence of symptoms, hyperacidity, and ulcer in 3 patients.

5. We feel that irradiation with cobalt-60 teletherapy may be indicated in many patients with complicated or so-called surgical ulcers, particularly in the bad-risk patients.

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The radioactive material used in this study was supplied on authorization of the Isotopes Division, United States Atomic Energy Commission, Oak Ridge, Tenn.

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Brown, C.H. Therapeutic principles in management of peptic ulcer. Digest Dis Sci 4, 1066–1072 (1959). https://doi.org/10.1007/BF02231507

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  • Public Health
  • Medical Treatment
  • Peptic Ulcer
  • Gastric Acid
  • Acid Secretion