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The effect of chlorothiazide on human gastric secretion

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Summary

In 12 of 18 studies on human gastric secretion a fall in free acid occurred after chlorothiazide was administered. In 3 of the 12 patients the decrease was definite, i.e., 60–100 per cent of basal secretion, in 4 the results equivocal, and in 5 the fall was not significant. The decrease in free acid was transient, lasting for 1 hour.

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References

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Kramer, P., Markarian, B. The effect of chlorothiazide on human gastric secretion. Digest Dis Sci 4, 130–136 (1959). https://doi.org/10.1007/BF02231233

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Keywords

  • Public Health
  • Free Acid
  • Gastric Secretion
  • Chlorothiazide
  • Basal Secretion