The American Journal of Digestive Diseases

, Volume 6, Issue 8, pp 742–756 | Cite as

Carcinoma of the esophagus as a complication of megaesophagus

An analysis of seven cases
  • L. H. Camara-Lopes


(1) In a period of 3½ years seven cases of carcinoma of the esophagus were seen in patients with megaesophagus of different durations. They are described fully.

(2) Attention is called to the fact that the tumor may occur at any level and therefore may be overlooked in a dilated esophagus, because it does not cause stenosis.

(3) Chronic esophagitis with ulceration of the mucosa owing to stasis and fermentation in the lumen of the esophagus is considered the most likely cause of cancer.

(4) The author advises early radical treatment for megaesophagus as a preventive measure against carcinoma, in view of the exceptional diagnostic difficulties found in long-standing cases of the disease.

(5) Subtotal esophagectomy with cervical esophagogastrostomy, bringing the stomach up to the neck through a substernal tunnel, is the author's method of choice for megaesophagus.


Public Health Carcinoma Radical Treatment Fermentation Preventive Measure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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    Breuil, N. La dégénérescence néoplastique dans le megaoesophage par cardiospasme. Thèse de Lyon, No. 155, 1957.Google Scholar
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    Camara-Lopes, L. H. Transposição retrosternal do estômago para anastomose esôfago-gástrica cervical, após esofagectomia subtotal. Apresentação de nóta prévia no Centro Médico de Ribeirão Preto, Setembro, 1955.Google Scholar
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    Fagge, C. H. Case of simple stenosis of oesophagus followed by epithelioma.Guy's Hosp. Rep. 17:413, 1872.Google Scholar

Copyright information

© Paul B. Hoeber, Inc., Medical Division of Harper & Brothers 1961

Authors and Affiliations

  • L. H. Camara-Lopes
    • 1
  1. 1.From the Department of Surgery, Faculty of MedicineUniversity of São PauloRibeirão Prêto, SPBrazil

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