Advertisement

Clinical Rheumatology

, Volume 15, Issue 4, pp 353–357 | Cite as

Does chlamydia trachomatis influence manifestations of lyme arthritis?

  • O. Lesnyak
  • L. Sokolova
  • T. Starikova
  • M. Fadeeva
  • Y. Beikin
Originals

Summary

Lyme arthritis, caused by the tick-borne spirochete Borrelia burgdorferi, produces typically intermittent episodes of arthritis of the larger joints, usually the knee joints. A number of patients, however, develop arthritis more closely resembling Reiter's syndrome, i.e., heel and ankle involvement. We studied the clinical features of ten patients who developed arthritis after a tick bite and who had shown erythema migrans and related it to the presence of evidence of Chlamydia trachomatis infection. Along with typical signs of Lyme arthritis we observed heel and ankle involvement. Chlamydia trachomatis was found in smears in 4 cases, whereas no patient had antichlamydial antibodies. However, evidence of Chlamydia trachomatis did not correlate with signs considered typical of Reiter's syndrome. Therefore, Lyme arthritis may have some arthritic manifestations resembling Reiter's syndrome, but this seems unrelated to the presence of Chlamydia trachomatis. Moreover, the arthritis is not associated with HLA-B27.

Key words

Borrelia Burgdorferi Chlamydia Trachomatis Lyme Arthritis Reiter's Syndrome 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Steere, A.C., Malawista, S.E., Snydman, D.R. et al. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum 1977, 20, 17.Google Scholar
  2. 2.
    Dekonenko, E.J., Steere, A.C., Berardi, U.P., Kravchuk, L.N. Lyme borreliosis in the Soviet Union: a cooperative US-USSR report. J Infect Dis 1988, 158, 748–753.PubMedGoogle Scholar
  3. 3.
    Steere, A.C. Clinical definitions and differential diagnosis of Lyme arthritis. Scand J Infect Dis Suppl 1991, 77, 51–54.PubMedGoogle Scholar
  4. 4.
    Herzer, P. Joint manifestations of Lyme borreliosis in Europe. Scand J Infect Dis Suppl 1991, 77, 55–63.PubMedGoogle Scholar
  5. 5.
    Rahn, D.W., Craft, J. Lyme disease. Rheum Dis Clin North Amer 1990, 16, 601–615.Google Scholar
  6. 6.
    Ciesielski, C.A., Markowitz, L.E., Harsley, R. et al. Lyme disease surveillance in the United States. 1983–1986. Rev Infect Dis Suppl 6 1989, 11, 1435–1441.Google Scholar
  7. 7.
    Stanek, G. The epidemiology of Borrelia burgdorferi infections. In: New Antibacterial Strategies. Proceedings of the 1st Symposium, Hertfordshire 1990, 19–29.Google Scholar
  8. 8.
    Prohaska, E., Kristoferitsch, W., Stanek, G. Spinal involvement in Lyme borreliosis. Zbl Bakt 1989 Suppl 18, 261–262.Google Scholar
  9. 9.
    Kinigadner, U., Mur, E., Most, J. et al. Borrelia infection as a possible cause of HLA-B27 negative sacroiliitis. J Rheumatol 1991, 18, 484–485.PubMedGoogle Scholar
  10. 10.
    Weyand, C.M., Goronzy, J.J. Immune responses to Borrelia burgdorferi in patients with reactive arthritis. Arthritis Rheum 1989, 32, 1057–1064.PubMedGoogle Scholar
  11. 11.
    Arnett, F. The Lyme spirochete: another cause of Reiter's syndrome? Arthritis Rheum 1989, 32, 1182–1184.PubMedGoogle Scholar
  12. 12.
    Shatkin, A. Chlamydial infections in Russia and former USSR. In: Proceedings of the Europ Soc for Chlamydia Research, Stockholm 1992, 283–285.Google Scholar
  13. 13.
    Steere, A.C., Schoen, R.T., Taylor, E. The clinical evolution of Lyme arthritis. Ann Intern Med 1987, 107, 725–731.PubMedGoogle Scholar

Copyright information

© Clinical Rheumatology 1996

Authors and Affiliations

  • O. Lesnyak
    • 3
  • L. Sokolova
    • 1
  • T. Starikova
    • 2
  • M. Fadeeva
    • 2
  • Y. Beikin
    • 2
  1. 1.Urals State Medical InstituteRussia
  2. 2.City Center of Labs Diagnostics of Female and Pediatrics PathologyYekaterinburgRussia
  3. 3.Candidate of Medical Sciences, Head of Lyme Disease Center, Regional Hospital No. 1YekaterinburgRussia

Personalised recommendations