Advertisement

Antonie van Leeuwenhoek

, Volume 35, Issue 1, pp 497–504 | Cite as

Isolation and identification of orsellinic acid and penicillic acid produced byPenicillium fennelliae Stolk

  • G. W. van Eijk
Article

Abstract

Fifteen days-old surface cultures ofPenicillium fennelliae Stolk grown on a modified Czapek medium were analyzed for the production of metabolites. The presence of orsellinic acid, orcinol and penicillic acid was proved by means of chromatographic and physicochemical methods.

Keywords

Physicochemical Method Surface Culture Orcinol Penicillic Acid Czapek Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alsberg, C. L. andBlack, O. F. 1913. Contributions to the study of maize deterioration; biochemical and toxicological investigations ofPenicillium puberulum andPenicillium sloloniferum. - U. S. Dept. Agric. Bureau Plant Ind. Bull. No. 270, 1–47.Google Scholar
  2. Bentley, R. andKeil, J. 1961. The role of acetate and malonate in the biosynthesis of penicillic acid. - Proc. Chem. Soc.1961: 111–112.Google Scholar
  3. Bentley, R. andKeil, J. G. 1962. Tetronic acid biosynthesis in molds. II. Formation of penicillic acid inPenicillium cyclopium. - J. Biol. Chem.237: 867–873.Google Scholar
  4. Bentley, R. andCampbell, I. M. 1968. Secondary metabolism of fungi, p. 415–489.In: M. Florkin and E. H. Stotz, [eds.], Comprehensive Biochemistry, Vol. 20. Metabolism of cyclic compounds. - Elsevier, Amsterdam.Google Scholar
  5. Birkinshaw, J. H., Oxford, A. E. andRaistrick, H. 1936. Penicillic acid, a metabolic product ofPenicillium puberulum Bainier andP. cyclopium Westling. - Biochem. J.30: 394–411.Google Scholar
  6. Birkinshaw, J. H. andGowlland, A. 1964. Production and biosynthesis of orsellinic acid byPenicillium madriti G. Smith. - Biochem. J.84: 342–347.Google Scholar
  7. Curtis, R. F., Harries, P. C., Hassall, C. H. andLevi, J. D. 1964. The biosynthesis of phenols. 5. The relationship of some phenolic metabolites of mutants ofAspergillus terreus Thom I. M. I. 16043. - Biochem. J.90: 43–51.Google Scholar
  8. Feigl, F. 1966. Spot tests in organic analysis, 7th English ed., p. 425. - Elsevier, Amsterdam.Google Scholar
  9. Ford, J. H., Johnson, A. R. andHinman, J. W. 1950. The structure of penicillic acid. - J. Am. Chem. Soc.72: 4529–4531.Google Scholar
  10. Grove, J. F. 1952. Infra-red spectroscopy and structural chemistry. Part III. Gladiolic acid. - J. Chem. Soc.1952: 3345–3354.Google Scholar
  11. Mosbach, K. 1959. Das Vorkommen von Orsellinsäure inChaetomium cochliodes. - Z. Naturforsch.14b: 69–70.Google Scholar
  12. Mosbach, K. 1960. Die Biosynthese der Orsellinsäure und Penicillinsäure. - Acta Chem. Scand.14: 457–464.Google Scholar
  13. Packter, N. M. 1965. Studies on the biosynthesis of quinones in fungi. Incorporation of 6-methylsalicylic acid into fumigatin and related compounds inAspergillus fumigatus I. M. I. 89.353. - Biochem. J.97: 321–332.Google Scholar
  14. Packter, N. M. andSteward, M. W. 1967. Studies on the biosynthesis of phenols in fungi. Biosynthesis of 3, 4 dimethoxy, 6- methyltoluquinol and gliorosein inGliocladium roseum. I. M. I. 93.065. - Biochem. J.102: 122–132.Google Scholar
  15. Pettersson, G. 1965. An orsellinic acid decarboxylase isolated fromGliocladium roseum. - Acta Chem. Scand.19: 2013–2021.Google Scholar
  16. Raphael, R. A. 1947. Compounds related to penicillic acid. Part II. Synthesis of dihydropenicillic acid. - J. Chem. Soc.1947: 805–808.Google Scholar
  17. Reio, L. 1959. A method for the paper-chromatographic separation and identification of phenol derivatives, mould metabolites and related compounds of biochemical interest, using a “reference system”. - Chromatog. Rev.1:39–74.Google Scholar
  18. Shibata, S., Natori, S. andUdagawa, S. 1964. List of fungal products, p. 17. - Charles C. Thomas, Springfield, U.S.A.Google Scholar
  19. Stolk, A. C. 1969. Four new species ofPenicillium. - Antonie van Leeuwenhoek35: 261–274.Google Scholar
  20. Wachmeister, C. A. 1958. Studies on the chemistry of lichens. XI. Structure of picrolichenic acid. - Acta Chem. Scand.12: 147–164.Google Scholar

Copyright information

© Swets & Zeitlinger 1969

Authors and Affiliations

  • G. W. van Eijk
    • 1
  1. 1.Centraalbureau voor SchimmelculturesBaarnThe Netherlands

Personalised recommendations