Digestive Diseases and Sciences

, Volume 40, Issue 8, pp 1845–1848 | Cite as

Liver injuries induced by herbal medicine, Syo-saiko-to (xiao-chai-hu-tang)

  • Susumu Itoh
  • Kazuhiro Marutani
  • Tatsushige Nishijima
  • Shuichi Matsuo
  • Motoya Itabashi
Liver: Infectious, Inflammatory, and Metabolic Disorders Case Report

Key Words

liver injury herbal medicine breath test 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Stillman AE, Huxtable R, Consroe P, Kohnen P, Smith S: Hepatic veno-occlusive disease due to pyrrolizidine (senecio) poisoning in Arizona. Gastroenterology 73:349–352, 1977Google Scholar
  2. 2.
    Hyde FF: Mistletoe hepatitis. Br Med J 282:739, 1981Google Scholar
  3. 3.
    Rottman JN: Comfrey and liver damage. Lancet 1:944, 1981Google Scholar
  4. 4.
    Anderson C: Comfrey in perspective. Lancet 1:1424, 1981Google Scholar
  5. 5.
    Kumana CR, Ng M, Lin HJ, Ko W, Wu P-C, Todd D: Hepatic veno-occlusive disease due to toxic alkaloid in herbal tea. Lancet 1:1360–1361, 1983Google Scholar
  6. 6.
    Mizoguchi Y, Yoshiyasu K, Tsutsui H, Myyajima K, Sakagami Y, Tojo T, Seki M, Yamamoto Y, Morisawa S: A case of drug-induced allergic hepatitis by herbal medicine. Acta Hepatol Jpn 27:238–241, 1986Google Scholar
  7. 7.
    Satake I, Maeda M, Koyama W, Sakamoto S, Koizumi S, Kanayama M: A case of hepatic injury caused by an herb drug. Acta Hepatol Jpn 27:238–241, 1986Google Scholar
  8. 8.
    Harvey J, Colin-Jones DG: Mistletoe hepatitis. Br Med J 282:186–187, 1981Google Scholar
  9. 9.
    MacGregor FB, Abernethy VE, Dahabra S, Cobden I, Hayes PC: Hepatotoxicity of herbal remedies. Br Med J 199:1156–1157, 1989Google Scholar
  10. 10.
    Weeks GR, Proper JS: Herbal medicines—gaps in our knowledge. Aust J Hosp Pharmacol 19:155–157, 1989Google Scholar
  11. 11.
    Carlsson C: Herbs and hepatitis. Lancet 2:1065, 1990Google Scholar
  12. 12.
    Larrey D, Vial T, Pauwels A, Castot A, Biour M, David M, Michel H: Hepatitis after germander (Teucrium chamaedrys) administration: Another instance of herbal medicine hepatotoxicity. Ann Intern Med 117:129–132, 1992Google Scholar
  13. 13.
    Marutani K, Nishijima T, Nishiyama J, Nemoto H, Matsuo S, Matsuyama Y, Itoh S: Changes in liver test results after stopping syo-saiko-to. Acta Hepatol Jpn 31(suppl):119, 1990Google Scholar
  14. 14.
    Marutani K, Matsuo S, Nishijima T, Watanobe T, Ishida Y, Sasaki K, Kameda C, Itoh S: Light and electron microscopic findings in the liver of five patients with syo-saiko-to-induced hepatitis. Jpn J Gastroenterol 87:640, 1990Google Scholar
  15. 15.
    Itabashi M: Clinical utility of13C-aminopyrine breath test in patients with chronic liver diseases. J Saitama Med School 18:261–268, 1991Google Scholar
  16. 16.
    Hepner GW, Vesell ES: Quantitative assessment of hepatic function by breath analysis after oral administration of [14C]aminopyrine. Ann Intern Med 83:632–638, 1975Google Scholar
  17. 17.
    Stricker BHCH, Block APR, Desmet VJ: Pathology of Drug-Induced Hepatic Injury, 2nd ed. Amsterdam, Elsevier, 1992, pp 51–70Google Scholar
  18. 18.
    Loeper J, Deseatoire V, Letteron P, Moulis C, Degott C, Dansette P, Fau D, Pessayre D: Hepatotoxicity of germander in mice. Gastroenterology 106:464–472, 1994Google Scholar
  19. 19.
    Keys JD: Chinese Herbs. Their Botany, Chemistry, and Pharmacodynamics. Rutland, Vermont, Charles E. Tuttle, 1976Google Scholar
  20. 20.
    De Smet PAGM:Scutellaria species.In Adverse Effects of Herbal Drugs, Vol 2. PAGM De Smet, K Keller, R Hänsel (eds). Berlin, Springer-Verlag, 1993, pp 289–296Google Scholar

Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • Susumu Itoh
    • 1
  • Kazuhiro Marutani
    • 1
  • Tatsushige Nishijima
    • 1
  • Shuichi Matsuo
    • 1
  • Motoya Itabashi
    • 1
  1. 1.Department of Medicine 3Saitama Medical SchoolIruma, SaitamaJapan

Personalised recommendations