Clinical Rheumatology

, Volume 14, Issue 4, pp 474–477

Ochronotic arthropathy: Rapid destructive hip osteoarthritis associated with metabolic disease

  • T. Corrà
  • M. Zaccala
  • M. Galante
Case Reports

DOI: 10.1007/BF02207686

Cite this article as:
Corrà, T., Zaccala, M. & Galante, M. Clin Rheumatol (1995) 14: 474. doi:10.1007/BF02207686

Summary

Ochronosis is a musculoskeletal manifestation of alkaptonuria, an inherited metabolic disorder associated with various systemic abnormalities related to the deposition of homogentisic acid pigment in connective tissues. This report describes a 58-year-old woman with ochronotic arthropathy who, in addition to the typical clinical features of the disorder, presented with rapidly progressive hip osteoarthritis. The destruction of the joint architecture and the severe functional impairment necessitated a total hip replacement which resulted in a satisfactory outcome.

Key words

Ochronotic Arthropathy Alkaptonuria Rapid Destructive Hip Osteoarthritis Ochronosis Homogentisic Acid 

Copyright information

© Acta Medica Belgica 1995

Authors and Affiliations

  • T. Corrà
    • 1
  • M. Zaccala
    • 1
  • M. Galante
    • 1
  1. 1.Department of Physical Therapy and Rehabilitation 'Clinica del Lavoro' FoundationInstitute of Care and ResearchVeruno, NovaraItaly

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