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Clinical Rheumatology

, Volume 10, Issue 2, pp 211–214 | Cite as

Histopathological findings in a case of systemic lupus erythematosus-associated anti-phospholipid syndrome

  • P. L. Meroni
  • R. Rivolta
  • P. Ghidoni
Case Report

Summary

The vessel anatomopathological lesions in a patient with systemic lupus erythematosus associated anti-phospholipid syndrome are described. Vasculitic lesions were nearly absent but small vessels showed hyalin thrombosis or substenosis due to subendothelial deposition of amorphous PAS-positive material in different anatomical districts. These findings can be related to the patient's clinical manifestations, particularly the central nervous system involvement and can be discussed regarding the possible pathogenetic mechanisms.

Key words

Anti-Phospholipid Syndrome Systemic Lupus Erythematosus Thrombosis 

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Copyright information

© Acta Medica Belgica 1991

Authors and Affiliations

  • P. L. Meroni
    • 1
  • R. Rivolta
    • 1
  • P. Ghidoni
    • 2
  1. 1.Istituto di Medicina InternaMalattie infettive ImmunopathologiaItaly
  2. 2.Istituto di Anatomia PatologicaUniversity of MilanItaly

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