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Archives of gynecology

, Volume 237, Issue 2, pp 101–107 | Cite as

Triploid embryo after in vitro fertilization

  • R. Ulmer
  • H. Rehder
  • S. Trotnow
  • A. Kniewald
  • T. Kniewald
  • R. A. Pfeiffer
Article

Summary

A case of a triploid embryo (69,XXX) resulting from in vitro fertilization is reported. The pregnancy ended in spontaneous abortion 44 days after embryo transfer. The embryo showed anomalies considered typical of triploidy but molar changes were not noted. The origin of extra chromosomes was apparently maternal.

Key words

Triploidy IVF Spontaneous abortion 

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References

  1. Boué JG, Boué A (1970) Les aberrations chromosomiques dans les avortements humains. Presse med 78:635–641Google Scholar
  2. Carr DH (1983) Cytogenetics of human reproductive wastage. In: Kalter H (ed) Issues and reviews in teratology, vol 1. Plenum Press, New YorkGoogle Scholar
  3. Jacobs PA, Angell RR, Buchanan IM, Hassold TJ, Matsuyama AM, Manuel B (1978) The origin of human triploids. Ann Hum Genet London 42:49–57Google Scholar
  4. Jacobs PA, Szulman AE, Funkhouser J, Matsuura JS, Wilson CC (1982) Human triploidy: relationship between parental origin of the additional haploid complement and development of partial hydatidiform mole. Ann Hum Genet 46:223–231Google Scholar
  5. Lauritsen JG, Bolund L, Friedrich U, Therkelsen AJ (1979) Origin of triploidy in spontaneous abortions. Ann Hum Genet 43:1–6Google Scholar
  6. Niebuhr E (1974) Triploidy in man. Cytogenetical and clinical aspects. Humangenetik 21: 103–125Google Scholar
  7. Rudak E, Dor J, Mashiach S, Nebel L, Goldmann B (1984) Chromosome analysis of multipronuclear human oocytes fertilized in vitro. Fertil Steril 41:538–545Google Scholar
  8. Seppälä M (1984) Own communicationGoogle Scholar
  9. Steptoe PC, Edwards RG, Purdy JM (1980) Clinical aspects of pregnancies established with cleaving embryos grown in vitro. Br J Obstet Gynecol 87:757–768Google Scholar
  10. Szulman AE, Philippe E, Boué JG, Boué A (1981) Human triploidy association with partial hydatidiform moles and non-molar conceptuses. Hum Pathol 12:1016–1021Google Scholar
  11. Trotnow S, Kniewald T, Hünlich T (1983) Die in vitro Fertilisation, ein neues Verfahren zur Sterilitätsbehandlung. Geburtshilfe Frauenheilkd 43:1–6Google Scholar

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • R. Ulmer
    • 1
  • H. Rehder
    • 3
  • S. Trotnow
    • 2
  • A. Kniewald
    • 1
  • T. Kniewald
    • 2
  • R. A. Pfeiffer
    • 1
  1. 1.Institut für Humangenetik (Direktor: Prof. Dr. R. A. Pfeiffer)ErlangenFederal Republic of Germany
  2. 2.Frauenklinik der Universität Erlangen-Nürnberg (Direktor: Prof. Dr. N. Lang)ErlangenFederal Republic of Germany
  3. 3.Institut für Pathologie derMedizinischen Hochschule Lübeck (Direktor: Prof. Dr. U. Löhrs)LübeckFederal Republic of Germany

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