, Volume 9, Issue 3, pp 248–252 | Cite as

Anticonvulsant properties of diacetylmonoxime (DAM) and its effect on the facilitatory action of reserpine on convulsions

  • Éva Galambos
  • A. Klára Pfeifer
Short Communications


Reserpine Anticonvulsant Property Facilitatory Action Diacetylmonoxime 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Balzer, H., P. Holtz u.D. Palm: Reserpin undγ-Aminobuttersäuregehalt des Gehirns. Experientia (Basel)17, 38–40 (1961).Google Scholar
  2. Bogdanski, D. F., A. Pletscher, B. B. Brodie, andS. Udenfiend: Identification and assay of serotonin in brain. J. Pharmacol. exp. ther.117, 82–88 (1956).Google Scholar
  3. Carlsson, A., andB. Waldeck: A fluorometric method for the determination of dopamine. Acta physiol. scand.44, 293–298 (1958).Google Scholar
  4. Euler, U. S. von, andF. Lishajko: The estimation of catecholamines in urine. Acta physiol. scand45, 122–132 (1959).Google Scholar
  5. Gaboural, J. D.: Anticonvulsant properties of diacetylmonoxime (DAM) Biochem. Pharmacol.5, 283–286 (1961).Google Scholar
  6. —, andJ. P. Comstock: Effect of diacetylmonoxime on the action of convulsant and sedative-hypnotic barbiturates. J. Pharmacol. exp. Ther.137, 122–126 (1962).Google Scholar
  7. Jenney, E.H., andC. C. Pfeiffer: The convulsant effect of hydrazides and the antidotal effect of anticonvulsants and metabolites. J. Pharmacol. exp. Ther.122, 110–123 (1958).Google Scholar
  8. Maynert, E. W., G. E. Klingman, andH. K. Kaji: Tolerance to morphine. II. Lack of effects on brain 5-HT and GABA. J. Pharmacol. exp. Ther.135, 296–299 (1962).Google Scholar
  9. Orloff, J. J., H. L. Williams, andV. C. Pfeiffer: Timed intravenous infusion of metrazol and strychnine for testing anticonvulsant drugs. Proc. Soc. exp. Biol. (N. Y.)70, 254–257 (1949).Google Scholar
  10. Pfeifer, A. Klára, Éva Sátory, andE. S. Vizi: Studies on the gutamic acid decarboxylase activity of rat brain in the state of inhibition following electroshock. J. Pharmacol. exp. Ther.138, 230–238 (1962).Google Scholar
  11. Shore, P. A., andJ. Olin: Identification and chemical assay of norepinephrine in brain and other tissues. J. Pharmacol. exp. Ther.122, 295–300 (1958).Google Scholar

Copyright information

© Springer-Verlag 1966

Authors and Affiliations

  • Éva Galambos
    • 1
  • A. Klára Pfeifer
    • 1
  1. 1.Department of PharmacologyInstitute for Experimental Medicine of the Hungarian Academy of SciencesBudapestHungary

Personalised recommendations