Plant Foods for Human Nutrition

, Volume 42, Issue 2, pp 143–151 | Cite as

Mineral balances in humans as affected by fructose, high fructose corn syrup and sucrose

  • Rao Ivaturi
  • Constance Kies


The utilization of selected minerals when sugars were supplemented to basal diets was investigated in two separate, laboratory-controlled human feeding studies. Fructose-fed subjects had higher fecal excretions of iron and magnesium than did subjects fed sucrose. Apparent iron, magnesium, calcium, and zinc balances tended to be less positive during the fructose feeding period as compared to balances during the sucrose feeding period. Conversely, high fructose corn syrup (HFCS) did not affect the mineral balances when compared to sucrose feeding. Subjects fed fructose experienced diarrhea which possibly decreased absorption of minerals and thus increased fecal mineral losses. No such adverse effects were noticed when HFCS was fed.

Key words

Sugars high-fructose corn syrup mineral bioutilization mineral availability sugars and mineral interactions 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Carmen HF, Thor PK (1979) High fructose corn syrup: economic aspects of a sugar substitute. Davis, University of California: 20–34Google Scholar
  2. 2.
    Brook EM (1977) High fructose corn syrup: its significance as a sugar substitute and its impact on the sugar. The World Bank Commodity Paper 25. Washington DC World Band: 2–21Google Scholar
  3. 3.
    Cardillo AV, Hunt D, Mann B (1979) Relative sweetness of fructose and sucrose in model solutions, lemon beverages, and white cake. J Food Sci 44: 748–751Google Scholar
  4. 4.
    Hodgkinson RA (1961) A comparative study of iron absorption and utilization following ferrous sulphate and sodium irondetate. Med J Australia 48: 809–813Google Scholar
  5. 5.
    Reiser S, Ferretti RJ, Fields M, Smith N (1983) Role of dietary fructose in the enhancement of mortality and biochemical changes associated with copper deficiency in rats. Am J Clin Nutr 38: 214–222Google Scholar
  6. 6.
    Meyer FL, Copper K, Bolick M (1972) Nitrogen and mineral excretion after carbohydrate test meals. Amer J Clin Nutr 25: 667–683Google Scholar
  7. 7.
    Scholz RW, Featherston WK (1967) Influece of lactose and glucose on magnesium-28 retention in the chick. J Nutr 91: 232–236Google Scholar
  8. 8.
    Entringer RP, Plumlee MP, Conrad JH, Cline TR, Wolfe S (1975) Influence of diet on passage rate and apparent digestibility by growing swine. J Anim Sci 40: 486–494Google Scholar
  9. 9.
    Wilson GF, Reid CSW, Malloy LF, Metson AJ, Butler GW (1969) Grass tetany: influence of starch and peanut oil supplements on plasma magnesium, calcium and phosphorus levels in grazing dairy cows. New Zealand J Agri Res 12: 467–472Google Scholar
  10. 10.
    Bates GWJ, Boyer J, Hegenaver JC, Saltman P (1972) Facilitation of iron absorption by ferric fructose. Am J Clin Nutr 25: 983–986Google Scholar
  11. 11.
    Folin O (1914) On the determination of creatinine and creatine in urine. J Biol Chem 17: 469Google Scholar
  12. 12.
    Fiske CH, Subbarow A (1925) The colorimetric determination of phosphorus. J Biol Chem 66: 375–400Google Scholar

Copyright information

© Kluwer Academic Publishers 1992

Authors and Affiliations

  • Rao Ivaturi
    • 1
  • Constance Kies
    • 2
  1. 1.Department of Home EconomicsIndiana State UniversityTerre HauteUSA
  2. 2.Department of Nutritional Science and Hospitality ManagementUniversity of NebraskaLincolnUSA

Personalised recommendations