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Pharmaceutisch weekblad

, Volume 3, Issue 1, pp 1098–1101 | Cite as

Separation of some fatty ointment excipients by gradient elution HPTLC

  • F. J. Van De Vaart
Article

Abstract

A very simple gradient elutionTlc system for the separation of some common fatty excipients of rather varying polarities in one run is presented. WhenHptlc precoated plates are used, run times are as short as 10 minutes. The system is useful as a simple quality control for fatty excipients, ointment bases and complete ointments.

Samenvatttng

Een eenvoudig dunnelaag-chromatografisch systeem met gradiënt-elutie voor de bepaling van enkele veel gebruikte vette hulpstoffen wordt beschreven. MetHptlc precoated plates kunnen Stoffen van uiteenlopende polariteit in één gang, binnen 10 minuten, worden gescheiden. Het systeem is bruikbaar voor eenvoudige kwaliteitscontrole van vette excipiënten, zalfbases en zalven.

Keywords

Propylene Glycol Triamcinolone Acetonide Clioquinol Ointment Base Thin Layer Chromato 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Tarr, G.E. (1970)J Chromatog. 52, 357–361.CrossRefGoogle Scholar
  2. Vinson, J.E., andJ.E. Hooyman (1977)J. Chromatog. 135, 226–228.CrossRefGoogle Scholar
  3. Zeeuw, R.A. De (1968) Ph.D. thesis. Groningen, The Netherlands.Google Scholar

Copyright information

© Bohn, Scheltema & Holkema 1981

Authors and Affiliations

  • F. J. Van De Vaart
    • 1
  1. 1.Laboratorium der Nederlandse ApothekersJL 's-Gravenhage

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