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Pharmaceutisch weekblad

, Volume 3, Issue 1, pp 810–814 | Cite as

Isolation and analytical aspects of Valeriana compounds

II. A statistical comparison of extraction procedures and of quantitative determinations of (iso)valtrate
  • B. Hazelhoff
  • B. Weert
  • Th. M. Malingré
Article

Abstract

A statistical comparison between the soxhlet extraction and the percolation extraction of (iso)valtrate from severalValeriana preparations did not show a significant difference with regard to their accuracy. Because the soxhlet extraction was the least laborious, this procedure was preferred. Thereafter a quantitative determination of (iso)valtrate was performed using TLC and HPLC.

The standard deviation of the values obtained by HPLC was found to be significantly smaller compared to the values obtained by TLC. Furthermore, the HPLC procedure turned out to be less laborious.

Keywords

HPLC Method Soxhlet Extraction Dual Wavelength Anisaldehyde Pharmaceutisch Weekblad Scientific Edition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Bohn, Scheltema & Holkema 1981

Authors and Affiliations

  • B. Hazelhoff
    • 1
  • B. Weert
    • 1
  • Th. M. Malingré
    • 1
  1. 1.Laboratory for PharmacognosyState University of GroningenAW GroningenThe Netherlands

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