Neuropsychological impairment in first-episode and chronic schizophrenic patients

  • M. Albus
  • W. Hubmann
  • Ch. Ehrenberg
  • U. Forcht
  • F. Mohr
  • N. Sobizack
  • Ch. Wahlheim
  • S. Hecht
Original Paper

Abstract

Patients with first-episode (FE) schizophrenia (n=40), with chronic schizophrenia (n=40) and healthy controls (n=40) matched for age, gender, education and parental socioeconomic status were administered a battery of standardized neuropsychological (NP) tests. Both patient groups showed generalized impairment relative to controls and the most pronounced deficits in visual-motor processing and attention (VSM). Compared with FE patients, chronic schizophrenics performed worse in VSM and abstraction/flexibility. Our findings suggest that NP deficits are fundamental manifestations of the illness, and that mainly frontally based dysfunctions are more prominent in chronic, kraepelinian patients.

Key words

Chronic schizophrenia First-episode schizophronia Neuropsychological testing Frontal dysfunction Temporohippocampal dysfunction 

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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • M. Albus
    • 1
  • W. Hubmann
    • 1
  • Ch. Ehrenberg
    • 1
  • U. Forcht
    • 1
  • F. Mohr
    • 1
  • N. Sobizack
    • 1
  • Ch. Wahlheim
    • 1
  • S. Hecht
    • 1
  1. 1.State Mental Hospital HaarHaarGermany

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