Commercial applications of algae: opportunities and constraints
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Microalgae have three fundamental attributes that can be converted into technical and commercial advantages:
They are genetically a very diverse group of organisms with a wide range of physiological and biochemical characteristics; thus they naturally produce many different and unusual fats, sugars, bioactive compounds, etc.
They can cost-effectively incorporate the stable isotopes13C,15N and2H into their biomass, and thus into various compounds they produce.
They comprise a large, unexplored group of organisms, and thus provide a virtually untapped source of products.
The challenge in the application of microalgae to commercial ends is to focus only on those products with large market and/or profit potential, where the use of microalgae leads to clear competitive advantages. This requires a clear understanding of the practical use of the microalgal product, the market it addresses, and its advantages and cost relative to competitive products or processes. Several examples are presented.
Key wordsmicroalgae algal products algal biotechnology
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- Appelt K and 31 other authors associated with Agouron Pharmaceuticals, Inc. (1991) Design of enzyme inhibitors using iterative protein crystallographic analysis. J. med. Chem. 34: 1925–1934.Google Scholar
- Barclay WR, Meager KM, Abril JR (1994) Heterotrophic production of long chain omega-3 fatty acids utilizing algae and algae-like microorganisms. J. appl. Phycol. 6: 123–129.Google Scholar
- Behrens PW, Bingham SE, Hoeksema SD, Cohoon DL, Cox JC (1989) Studies on the incorporation of CO2 into starch byChlorella vulgaris. J. appl. Phycol. 1: 123–130.Google Scholar
- Bold HC, Wynne MJ (1985) Introduction to the Algae. Structure and Reproduction. Prentice-Hall, Inc., Englewood Cliffs, N.J., 720 pp.Google Scholar
- Crueger W, Crueger A (1989) Biotechnology: A Textbook of Industrial Microbiology, 2nd edn. Sinauer Associates, Sunderland, Mass., 357 pp.Google Scholar
- Friedmann EI, Nienow JA, McKay CP (1988) The cryptoendolithic microbial environment in the Ross Desert of Antarctica: Light in the photosynthetically active region. Microbial Ecol. 16: 271–289.Google Scholar
- Hecht J (1993) Animals and fungi closer than anyone expected. New Sci. No. 1877: 16.Google Scholar
- Hsu U, Armitage I (1992) Solution structure of cyclosporin A and a nonimmunosuppressive analog bound to fully deuterated cyclophilin. Biochemistry 31 (51): 12778–12784.Google Scholar
- Kaplan D, Richmond AE, Dubinsky Z, Aaronson S (1986) Algal nutrition. In Richmond A (ed.), Handbook of Microalgal Mass Culture, CRC Press, Boca Raton: 147–198.Google Scholar
- Kay LE, Clore GM, Bax A, Gronenborn AM (1990) Four-dimensional heteronuclear triple-resonance NMR spectroscopy of interleukin-1 in solution. Science 249: 411–414.Google Scholar
- King CE, Toskes PP (1986) Comparison of the 1-gram [14C]xylose, 10-gram lactulose-H2, and 80-gram glucose-H2 breath tests in patients with small intestine bacterial overgrowth. Gastroenterology 91: 1447–1451.Google Scholar
- Kok B (1960) Efficiency of photosynthesis. In Ruhland W (ed.), Encyclopedia of Plant Physiology. Vol. 5: The Assimilation of Carbon Dioxide. Springer-Verlag, Berlin: 566–633.Google Scholar
- Kyle DJ, Boswell KDB, Gladue RM, Reeb SE (1992) Designer oils from microalgae as nutritional supplements. In Bills DB, Kung S (eds), Biotechnology and Nutrition, Proceedings of the 3rd International Symposium. Butterworth-Heinemann, Boston, 468 pp.Google Scholar
- Lands WEM (1986) Fish and Human Health. Academic Press, Orlando.Google Scholar
- Lee RE (1989) Phycology. 2nd edn. Cambridge University Press, Cambridge, 170 pp.Google Scholar
- Neuringer M, Conner WE (1987) The importance of dietary n-3 fatty acids in the development of the retina and nervous system. In Lands WEM (ed.), Proc. of the AOCS Short Course on Polyunsaturated Fatty Acids and Eicosanoids. American Oil Chemists Society, Champaign, Illinois, 574 pp.Google Scholar
- Nybakken JW (1982) Marine Biology: An Ecological Approach. Harper & Row Publishers, New York, 446 pp.Google Scholar
- O'Colla PS (1962) Mucilages. In Lewin RA (ed.), Physiology and Biochemistry of Algae. Academic Press, New York: 337–356.Google Scholar
- Pohl P (1982) Lipids and fatty acids of microalgae. In Zaborsky (ed.), Handbook of Biosolar Resources. CRC Press, Boca Raton: 383–404.Google Scholar
- Radmer RJ, Kok B (1977) Light conversion efficiency in photosynthesis. In Trebst A, Avron M (eds), Encyclopedia of Plant Physiology, New series, Vol 5. Springer-Verlag, Berlin: 125–135.Google Scholar
- Raven PH, Evert RF, Eichorn SE (1992) Biology of Plants, 5th ed., Worth Publishers, New York, 791 pp.Google Scholar
- Schoeller DA, Schneider JF, Solomons NW, Watkins JB, Klein PD (1977) Clinical diagnosis with stable isotope13C in CO2 breath tests: Methodology and fundamental considerations. J. lab. clin. Med. 90: 412–421.Google Scholar
- Shimizu Y (1993) Dinoflagellates as sources of bioactive molecules. In Attaway DH, Zaborsky OR (eds), Marine Biotechnology, Vol. 1, Pharmaceutical and Bioactive Natural Products. Plenum Press, New York: 391–410.Google Scholar
- Shreeve WW, Shoop JD, Ott DG, McInteer BB (1976) Test for alcoholic cirrhosis by conversion of [14C] or [13C]galactose to expired CO2. Gastroenterology 71: 98–101.Google Scholar
- Suzuki T, Mori H, Yamane T, Shimizu S (1985) Automatic supplementation of minerals in fed-batch culture to high cell mass concentration. Biotech. Bioeng. 27: 192–201.Google Scholar
- Wainright PO, Hinkle G, Sogin ML, Stickel SK (1993) Monophyletic origins of the metazoa: An evolutionary link with the fungi. Science 260: 340–342.Google Scholar