Human Genetics

, Volume 97, Issue 3, pp 399–403

Integration of four genes, a pseudogene, thirty-one STSs, and a highly polymorphic STRP into the 7–10 Mb YAC contig of 5q34–q35

  • Markus Kostrzewa
  • Deborah L. Grady
  • Robert K. Moyzis
  • Lars Flöter
  • Ulrich Müller
Rapid Communication

Abstract

Thirty-one sequence tagged sites and a highly polymorphic short tandem repeat polymorphism have been isolated from 5q34–q35 and integrated into the yeast artificial chromosome (YAC) contig of 5q34–q35. In addition, four genes (MSX2, CSX, DRDI, andCLI00) and a pseudogene (GLUT6) were localized on this map. The high density of new markers in the region allowed further refinement of the YAC contig of distal 5q. This is a prerequisite for the conversion of this YAC into a cosmid contig.

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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Markus Kostrzewa
    • 1
  • Deborah L. Grady
    • 2
  • Robert K. Moyzis
    • 2
  • Lars Flöter
    • 2
  • Ulrich Müller
    • 2
  1. 1.Institut für HumangenetikJustus-Liebig-UniversitätGiessenGermany
  2. 2.Los Alamos National Laboratory, MS-M885Center for Human Genome StudiesLos AlamosUSA

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