Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

In vitro antimicrobial susceptibility ofListeria monocytogenes isolated in the UK and otherListeria species

Abstract

The MICs and MBCs of 21 antimicrobial agents were determined for 103 strains ofListeria monocytogenes isolated in the UK and 27 strains of otherListeria species. Ampicillin, penicillin, azlocillin, imipenem, gentamicin, netilmicin, amikacin, erythromycin, rifampicin, trimethoprim, clindamycin and vancomycin had good activity, while cephalothin, chloramphenicol, ciprofloxacin and ofloxacin were less active, and cefuroxime, enoxacin, norfloxacin and fosfomycin were the least active. Tetracycline had good activity against many strains, but the MIC was high for some. Unlike the otherListeria species tested,Listeria ivanovii was susceptible to fosfomycin. Inoculum size and media employed were shown to affect the MBC, tryptose phosphate broth yielding higher MBCs than Mueller-Hinton or Isosensitest broths.

This is a preview of subscription content, log in to check access.

References

  1. 1.

    Wiggins GL, Albritton WL, Feeley JC: Antibiotic susceptibility of clinical isolates ofListeria monocytogenes. Antimicrobial Agents and Chemotherapy 1978, 13: 854–860.

  2. 2.

    Reynard AE, Espaze EP, Papi S, Courtier AI: Etude de la sensibilité aux antibiotiques de 139 souches deListeria serotypées par le Centre National de Reference en 1983. Annales de l'Institut Pasteur: Microbiologie 1984, 135B: 331–339.

  3. 3.

    Larsson S, Walker MM, Cronberg SN, Forsgren AB, Moestroop T: Antimicrobial susceptibilities ofListeria monocytogenes strains isolated from 1958–1982 in Sweden. Antimicrobial Agents and Chemotherapy 1985, 28: 12–13.

  4. 4.

    Reeves DS, Holt HA, Bywater MJ: In vitro study of fosfomycin trometamol. In: Neu HC, Williams JD (ed): New trends in urinary tract infection. Karger, Basel, 1987, p. 224–231.

  5. 5.

    Sabath LD, Wheeler N, Laverdreve M, Blazeric D, Wilkinson B: A new type of penicillin resistance ofStaphylococcus aureus. Lancet 1977, i: 443–447.

  6. 6.

    Rolston KV, Bodey GP: Activity of new antimicrobial agents againstListeria monocytogenes. European Journal of Clinical Microbiology 1987, 6: 686–688.

  7. 7.

    Hawkins AE, Borblussi R, Issekutz AC: In vitro and in vivo activity of various antibiotics againstListeria monocytogenes type 4b. Clinical and Investigative Medicine 1984, 7: 335–341.

  8. 8.

    Venglarak JS, Blair W, Bunkle LM: pH-dependent oxacillin tolerance ofStaphylococcus aureus. Antimicrobial Agents and Chemotherapy 1983, 23: 232–235.

Download references

Author information

Correspondence to A. P. MacGowan.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MacGowan, A.P., Holt, H.A., Bywater, M.J. et al. In vitro antimicrobial susceptibility ofListeria monocytogenes isolated in the UK and otherListeria species. Eur. J. Clin. Microbiol. Infect. Dis. 9, 767–770 (1990). https://doi.org/10.1007/BF02184692

Download citation

Keywords

  • Vancomycin
  • Ofloxacin
  • Clindamycin
  • Amikacin
  • Trimethoprim