Journal of Autism and Developmental Disorders

, Volume 25, Issue 5, pp 521–539 | Cite as

Sensory modulation of auditory stimuli in children with Autism And Receptive Developmental Language Disorder: Event-related brain potential evidence

  • Alan J. Lincoln
  • Erich Courchesne
  • Lisa Harms
  • Mark Allen
Article

Abstract

Three groups of age- and PIQ-matched children (Autism, Receptive Developmental Language Disorder, and normal controls) participated in two eventrelated brain potential (ERP) experiments. Each of these experiments was aimed at evaluating whether either of the two clinical groups of children demonstrated abnormalities in two auditory ERP components, Nl and P2, which are known to be dependent on stimulus characteristics (frequency, intensity, and probability), and believed to be generated within primary and secondary cortex. Results of Experiment 1 provide partial support for the idea that both clinical groups failed to fully process changes in stimulus intensity as indexed by the N1 component. Results are discussed in reference to potential abnormalities in serotonergic regulation of auditory cortex.

Keywords

Normal Control School Psychology Auditory Stimulus Stimulus Intensity Sensory Modulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • Alan J. Lincoln
    • 1
    • 2
  • Erich Courchesne
    • 1
    • 3
  • Lisa Harms
    • 1
  • Mark Allen
    • 1
    • 2
  1. 1.Neuropsychology Research LaboratoryChildren's HospitalSan Diego
  2. 2.California School of Professional PsychologyUSA
  3. 3.Department of NeurosciencesUniversity of California at San DiegoUSA

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