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Kinetic examination of ligand exchange reaction between99mTc-gluconate and dimercaptosuccinic acid

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Abstract

99mTc-dimercaptosuccinic acid is one of the most widely applied radiopharmaceutical for renal scintigraphy. This complex was prepared by ligand exchange reaction from99mTc-gluconate at tracer concentration of technetium under acidic conditions. The exchange yield was determined by paper chromatography and reaction rate constants were calculated at different pH values.

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Imre, J. Kinetic examination of ligand exchange reaction between99mTc-gluconate and dimercaptosuccinic acid. Journal of Radioanalytical and Nuclear Chemistry Letters 87, 291–300 (1984). https://doi.org/10.1007/BF02165935

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Keywords

  • Chromatography
  • Physical Chemistry
  • Inorganic Chemistry
  • Exchange Reaction
  • Acidic Condition